24309-78-2

Basic information

• Product Name: 2,4-dichloro-N,N-diethylbenzamide
• CAS NO: 24309-78-2
• Molecular Formula: C₁₁H₁₃Cl₂NO
• Molecular Weight: 246.133
• Mol File: 24309-78-2.mol

Chemical Properties

• Boiling Point: 370.3°C at 760 mmHg
• Flash Point: 177.8°C
• Density: 1.22g/cm³
• Vapor Pressure: 1.12E-05mmHg at 25°C
• Refractive Index: 1.544
• CAS DataBase Reference: 2,4-dichloro-N,N-diethylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dichloro-N,N-diethylbenzamide(24309-78-2)
• EPA Substance Registry System: 2,4-dichloro-N,N-diethylbenzamide(24309-78-2)

Safety Data

• Hazardous Substances Data: 24309-78-2(Hazardous Substances Data)

Usage

Uses

Used in Household Insect Repellents:
2,4-dichloro-N,N-diethylbenzamide is used as an active ingredient in household insect repellents for its ability to deter insects from entering living spaces, providing protection against insect-borne diseases and discomfort.
Used in Agricultural Insecticides:
In the agricultural industry, 2,4-dichloro-N,N-diethylbenzamide is used as an insecticide to protect crops from insect damage. Its application helps maintain crop yield and quality by reducing the impact of pests on plants.
Safety Precautions:
It is crucial to use 2,4-dichloro-N,N-diethylbenzamide with caution and adhere to proper safety guidelines. The chemical can be toxic to humans and animals if ingested or inhaled in large quantities, necessitating careful handling and storage to prevent accidental exposure.

Upstream product

• 109-89-7 diethylamine 
• 89-75-8 2,4-dichlorobenzoyl chloride 
• 13014-18-1 2,4-dichlorobenzotrichloride 
• 121-44-8 triethylamine 

Downstream Products

• 873845-88-6 2-chloro-N,N-diethyl-4-propylbenzamide 

Relevant articles and documents

One-Pot Synthesis of Tertiary Amides from Organic Trichlorides through Oxygen Atom Incorporation from Air by Convergent Paired Electrolysis

A convergent paired electrolysis catalyzed by a B12 complex for the one-pot synthesis of a tertiary amide from organic trichlorides (R-CCl3) has been developed. Various readily available organic trichlorides, such as benzotrichloride and its derivatives, chloroform, dichlorodiphenyltrichloroethane (DDT), trichloro-2,2,2-trifluoroethane (CFC-113a), and trichloroacetonitrile (CNCCl3), were converted to amides in the presence of tertiary amines through oxygen incorporation from air at room temperature. The amide formation mechanism in the paired electrolysis, which was mediated by a cobalt complex, was proposed.

Visible light-driven photocatalytic duet reaction catalyzed by the B12-rhodium-titanium oxide hybrid catalyst

The hybrid catalyst composed of the B12 complex and rhodium ion (Rh3+) modified titanium oxide was synthesized for the visible light-driven B12 inspired catalytic reaction. The hybrid catalyst contains 4.93 × 10?6 molg?1 of the B12 complex and 5.43 × 10?5 molg?1 of the Rh(III) ion on the surface of titanium oxide. Visible light irradiation (λ ≧ 420 nm) of the hybrid catalyst in the presence of triethylamine (Et3N) as a sacrificial reagent showed absorption at 390 nm, typical for the Co(I) state of the B12 complex monitored by diffuse reflectance UV–vis analysis, which imply that electron transfer from the titanium oxide to Co(III) center of the B12 complex occurred by the visible light irradiation. Benzotrichloride was converted to N,N-diethylbenzamide by the visible light irradiation catalyzed by the hybrid catalyst in air at room temperature. Both the conduction band electron and valence band hole of the catalyst were utilized for the reaction to form the amide product. The reaction mechanism of the duet reaction was proposed.

Visible Light-Driven, One-pot Amide Synthesis Catalyzed by the B12 Model Complex under Aerobic Conditions

A visible light responsive catalytic system with the B12 complex as the catalyst and [Ir(dtbbpy)(ppy)2]PF6 as the photosensitizer was developed. It provides a convenient and efficient way to synthesize amides. Based on this method, trichlorinated organic compounds were converted into amides in the presence of an amine under aerobic conditions at room temperature in a one-pot procedure. Various trichlorinated organic compounds and an amine source, such as primary, secondary, and cyclic amines, have been evaluated for this transformation, providing the expected products in moderate to excellent yields. Notably, product formation depended on the reaction atmosphere where the amide was obtained under aerobic conditions while partially dechlorinated products were obtained under anaerobic conditions. As this protocol is free from hazardous reagents, extra additives, noble metals, and dangerous gas, the present method provides a novel and efficient approach for amide synthesis under mild and easily controlled conditions.

Development of an acyl sulfonamide anti-proliferative agent, ly573636 ? na

The synthesis of 5-bromo-thiophene-2-sulfonic acid 2,4-dichlo- robenzoylamide sodium salt on multikilogram scale is described. The initial clinical supplies were made using carbonyl diimidazole to converge the two fragments. A more efficient acid chloride process has been developed, which also provides better control of impurities and color throughout the synthesis.