245743-64-0

Basic information

• Product Name: methyl 5-chloro-2-fluoro-4-hydroxybenzoate
• Synonyms: methyl 5-chloro-2-fluoro-4-hydroxybenzoate
• CAS NO: 245743-64-0
• Molecular Formula: C₈H₆ClFO₃
• Molecular Weight: 204.5828432
• EINECS: -0
• Mol File: 245743-64-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: methyl 5-chloro-2-fluoro-4-hydroxybenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-chloro-2-fluoro-4-hydroxybenzoate(245743-64-0)
• EPA Substance Registry System: methyl 5-chloro-2-fluoro-4-hydroxybenzoate(245743-64-0)

Safety Data

• Hazardous Substances Data: 245743-64-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Methyl 5-chloro-2-fluoro-4-hydroxybenzoate is used as an active pharmaceutical ingredient for its antimicrobial and anti-inflammatory properties. It aids in the development of medications targeting a range of conditions, including bacterial and inflammatory disorders.
Used in Industrial Chemical Production:
methyl 5-chloro-2-fluoro-4-hydroxybenzoate is utilized as an intermediate in the synthesis of other industrial chemicals. Its unique properties allow it to be a key component in the creation of various chemical products used across different industries.
Used as a Pesticide:
Methyl 5-chloro-2-fluoro-4-hydroxybenzoate is used as a pesticide due to its ability to inhibit the growth of microorganisms. Its application helps protect crops and enhance agricultural productivity by controlling pests and diseases.
Used as a Fungicide:
Similarly, this compound is employed as a fungicide, leveraging its antimicrobial properties to prevent the growth of fungi that can damage crops and other plants. This use contributes to the overall health and yield of agricultural products.

Upstream product

• 197507-22-5 methyl 2-fluoro-4-hydroxybenzoate 
• 67-56-1 methanol 
• 593280-19-4 5-chloro-2-fluoro-4-hydroxy-benzoic acid 
• 65145-13-3 2-fluoro-4-hydroxybenzoic acid 
• 245743-63-9 methyl 5-chloro-4-methoxy-2-nitrobenzoate 
• 74127-07-4 5-chloro-4-methoxy-2-nitrobenzoic acid 
• 130017-52-6 5-acetylamino-4-methoxy-2-nitrobenzoic acid 
• 204254-70-6 5-amino-4-methoxy-2-nitro-benzoic acid 
• 211172-73-5 methyl 5-chloro-2-fluoro-4-methoxybenzoate 
• 211172-72-4 5-chloro-2-fluoro-4-methoxybenzoic acid 
• 79025-26-6 methyl 2-amino-5-chloro-4-methoxybenzoate 

Downstream Products

• 211172-74-6 (R)-5-chloro-2-fluoro-4-(2-octyloxy)benzoate 

Relevant articles and documents

NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS

The present invention discloses compounds according to Formula (I) Wherein R1, R2, L, A1, A2, A3, Cy and the subscript n are as defined herein. The present invention relates to antagonists compounds of sphingosine 1-phosphate (SIP) receptor, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of diseases involving fibrotic diseases, inflammatory diseases, respiratory diseases, autoimmune diseases, metabolic diseases, cardiovascular diseases, and/or proliferative diseases by administering the compound of the invention.

N-SULFONYL BENZAMIDE DERIVATIVE WITH HETEROCYCLIC SUBSTITUENT, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF

The present invention discloses an N-sulfonyl benzamide derivative with a heterocyclic substituent, and a preparation method therefor and a pharmaceutical application thereof. More specifically, the invention discloses a compound represented by formula (II) or a pharmaceutically acceptable salt, stereoisomer, solvent compound, or prodrug thereof, and a preparation method therefor and an application thereof. Refer to the specification for definitions of each group in the formula.

Compounds and methods for doping liquid crystal hosts

This invention provides chiral thioindigo compounds for doping smectic liquid crystal hosts, wherein the compounds modulate a chiral bulk property of an induced chiral smectic liquid crystal phase upon irradiation at a wavelength in the visible range. Modulation of the chiral bulk property is effected by reversible trans-cis photoisomerization of the compound upon irradiation. The compounds maintain their rod-like shape in both isomeric forms, and hence do not destabilize the chiral smectic liquid crystal phase. Compounds according to the invention are useful in optical devices such as optical switches, displays, and memory.

Design of photonic liquid crystal materials: Synthesis and evaluation of new chiral thioindigo dopants designed to photomodulate the spontaneous polarization of ferroelectric liquid crystals

Irradiation of a ferroelectric S(c)* liquid crystal phase induced by the photochromic dopants (R,R)-6,6'-bis(2-octyloxy)-5,5'-dinitrothioindigo and (R,R)-5,5'-dichloro-6,6'-bis(2-octyloxy)thioindigo at λ=514 and 532 nm, respectively, causes an increase in spontaneous polarization (P(s)) by a factor ranging from 1.4 to 4.0. This increase in P(s) is achieved without concomitant destabilization of the S(c)* phase, and is consistent with an increase in transverse dipole moment of the thioindigo core as a result of trans-cis photoisomerization. The contribution of the thioindigo core towards P(s) is achieved through stereo-polar coupling with the chiral side-chains, which is enhanced by the presence of the nitro and chloro substituents.