- METHOD FOR PRODUCING DIOL
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PROBLEM TO BE SOLVED: To provide a method for producing a diol having two methylol groups at one carbon atom on an alicyclic skeleton, which is inexpensive and generates a small amount of waste. SOLUTION: There is provided a method for producing a diol re
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Paragraph 0049; 0050
(2019/03/08)
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- A convenient one-pot synthesis of 2,2-dialkyl-2,3-dihydro-1H-naphtho[2,1-b] pyrans
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This work describes a convenient one-pot procedure for the synthesis of 2,2-disubstituted 2,3-dihydro-177-naphtho[2,1-b]pyrans {i.e. 2,2-disubstituted 1H-benzo[f]chromans} by the reaction of 2-tetralones and α,α- disubstituted β-hydroxy propionaldehydes under acidic conditions. Georg Thieme Verlag Stuttgart.
- Jha, Amitabh,Huang, Po-Jung Jimmy,Mukherjee, Chandrani,Paul, Nawal K.
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p. 3127 - 3130
(2008/09/19)
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- Novel benzothiepines having activity as inhibitors of lleal bile acid transport and taurocholate uptake
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Provided are novel benzothiepines, derivatives, and analogs thereof; pharmaceutical compositions containing them; and methods of using these compounds and compositions in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions such as those associated with atherosclerosis or hypercholesterolemia, in mammals.
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- Novel benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
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Provided are novel benzothiepines, derivatives, and analogs thereof; pharmaceutical compositions containing them; and methods of using these compounds and compositions in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions such as those associated with atherosclerosis or hypercholesterolemia, in mammals.
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- Benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
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Provided are novel benzothiepines, derivatives, and analogs thereof; pharmaceutical compositions containing them; and methods of using these compounds and compositions in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions such as those associated with atherosclerosis or hypercholesterolemia, in mammals.
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- Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors
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Provided are novel benzothiepines, derivatives, and analogs thereof; pharmaceutical compositions containing them; and methods of using these compounds and compositions in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions such as those associated with atherosclerosis or hypercholesterolemia, in mammals. Also provided are compositions and methods for combination therapy employing ileal bile acid transport inhibitors and EG Co-A reductase inhibitors for the treatment of hyperlipidemic conditions.
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- Substituted 5-aryl-benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
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Provided are novel benzothiepines, derivatives, and analogs thereof; pharmaceutical compositions containing them; and methods of using these compounds and compositions in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions such as those associated with atherosclerosis or hypercholesterolemia, in mammals.
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- Benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
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Provided are novel benzothiepines, derivatives, and analogs thereof; pharmaceutical compositions containing them; and methods of using these compounds and compositions in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions such as those associated with atherosclerosis or hypercholesterolemia, in mammals.
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