250592-93-9

Basic information

• Product Name: 4-bromo-2-(4,5-dihydro-1,2-oxazol-3-yl)-3-methylaniline
• Synonyms: 4-Bromo-2-(4,5-dihydro-1,2-oxazol-3-yl)-3-methylaniline; benzenamine, 4-bromo-2-(4,5-dihydro-3-isoxazolyl)-3-methyl-
• CAS NO: 250592-93-9
• Molecular Formula: C₁₀H₁₁BrN₂O
• Molecular Weight: 255.1111
• EINECS: 607-517-6
• Mol File: 250592-93-9.mol

Chemical Properties

• Boiling Point: 349.431°C at 760 mmHg
• Flash Point: 165.13°C
• Density: 1.633g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.654
• CAS DataBase Reference: 4-bromo-2-(4,5-dihydro-1,2-oxazol-3-yl)-3-methylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-2-(4,5-dihydro-1,2-oxazol-3-yl)-3-methylaniline(250592-93-9)
• EPA Substance Registry System: 4-bromo-2-(4,5-dihydro-1,2-oxazol-3-yl)-3-methylaniline(250592-93-9)

Safety Data

• Hazardous Substances Data: 250592-93-9(Hazardous Substances Data)

Upstream product

• 250592-89-3 3-(2-methyl-6-aminophenyl)-4,5-dihydroisoxazole 

Downstream Products

• 250592-92-8 4-methylthio-3-(4,5-dihydroisoxazol-3-yl)-2-methylbromobenzene 
• 250592-94-0 4-Bromo-2-(4,5-dihydroisoxazol-3-yl)-3-methylbenzenesulfonyl Chloride 
• 71-36-3 butan-1-ol 

Relevant articles and documents

Preparation of 4-bromoaniline derivatives

A process for preparing 4-bromoaniline derivatives of the formula I where: R1is C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-alkoxy, C1-C6-haloalkoxy, C3-

Method and novel intermediate products for producing isoxazolin-3-yl-acylbenzenenes

The present invention describes a process for preparing isoxazoles of the formula I where: R1is hydrogen, C1-C6-alkyl, R2is hydrogen, C1-C6-alkyl, R3, R4, R5are each hydrogen, C1-C6-alkyl or R4and R5together from a bond, R6is a heterocysclic ring, n is 0, 1 or 2; which comprises preparing an intermediate of the formula VI where R1, R3, R4and R5are each as defined above, followed by halogenation, thiomethylation, oxidation and acylation to give compounds of the formula I. Furthermore, the invention describes novel intermediates for preparing the compounds of the formula I and novel processes for preparing the intermediates.