250592-92-8

Basic information

• Product Name: Isoxazole, 3-[3-bromo-2-methyl-6-(methylthio)phenyl]-4,5-dihydro-
• Synonyms: 4-methylthio-3-(4,5-dihydroisoxazol-3-yl)-2-methylbromobenzene;3-(3-bromo-2-methyl-6-methylthiophenyl)-4,5-dihydroisoxazole;Isoxazole,3-[3-bromo-2-methyl-6-(methylthio)phenyl]-4,5-dihydro
• CAS NO: 250592-92-8
• Molecular Formula: C11H12BrNOS
• Molecular Weight: 286.192
• Mol File: 250592-92-8.mol

Chemical Properties

• Boiling Point: 354.1±52.0 °C(Predicted)
• Density: 1.51±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Isoxazole, 3-[3-bromo-2-methyl-6-(methylthio)phenyl]-4,5-dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: Isoxazole, 3-[3-bromo-2-methyl-6-(methylthio)phenyl]-4,5-dihydro-(250592-92-8)
• EPA Substance Registry System: Isoxazole, 3-[3-bromo-2-methyl-6-(methylthio)phenyl]-4,5-dihydro-(250592-92-8)

Safety Data

• Hazardous Substances Data: 250592-92-8(Hazardous Substances Data)

Upstream product

• 250592-93-9 4-bromo-2-(4,5-dihydroisoxazol-3-yl)-3-methylaniline 
• 544-16-1 n-Butyl nitrite 
• 624-92-0 Dimethyldisulphide 
• 1885-76-3 2-cyano-3-nitrotoluene 
• 74-85-1 ethene 
• 391200-06-9 3-bromo-2-methyl-6-methylthiobenzonitrile 
• 12775-96-1 copper 

Downstream Products

• 247922-29-8 3-(3-bromo-2-methyl-6-(methylsulfonyl)phenyl)-4,5-dihydroisoxazole 
• 223646-24-0 3-(4,5-dihydroisoxazol-3-yl)-4-methylsulfonyl-2-methylbenzoic acid 

Relevant articles and documents

Method for recycling byproducts in synthesis of diphenyl sulfide compound

The invention provides a method for recycling byproducts in synthesis of a diphenyl sulfide compound. The byproducts comprise alkyl alcohol and dimethyl disulfide. The method comprises the steps of (1) mixing the byproducts in synthesis of the diphenyl sulfide compound with a sodium nitrite aqueous solution, adding concentrated hydrochloric acid for reaction, and obtaining alkyl nitrite and dimethyl disulfide; and (2) mixing the products obtained in the step (1) with copper powder, adding an aniline compound for reaction, carrying out desolvation treatment on the obtained reaction solution toobtain a diphenyl sulfide compound and byproducts, and returning the byproducts to the step (1). According to the recycling method, the byproducts do not need to be separated, the byproducts serve asraw materials to be directly applied to synthesis of the diphenyl sulfide compound, the process steps are simple and safe, cyclic utilization of the materials is achieved, and the raw material cost ofindustrial production of the diphenyl sulfide compound and the treatment cost of industrial three wastes are remarkably reduced.

Preparation method of 3-substituted phenyl-4,5-dihydroisoxazole derivative and application and intermediate thereof

The invention relates to a preparation method of a 3-substituted phenyl-4,5-dihydroisoxazole derivative and application and an intermediate thereof. A cyano compound (V) is converted into an N-hydroxybenzimidium compound (VII), and then 3-substituted phenyl-4,5-dihydroisoxazole intermediate (IX) is synthesized through a diazotization chlorination reaction and a dipolar cycloaddition reaction; a reaction condition is mild and controllable, the reaction selectivity in each step is good, the yield is relatively high, production of some byproducts is avoided, the product quality is guaranteed, andindustrialization of a whole technological route is easy to implement.

Preparation of -4-thioalkybrobenzene derivatives

A process for preparing 4-thioalkylbromobenzene derivatives of the formula I where: R1 is C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-alkoxy, C1-C6-haloalkoxy, Csu

Preparation of 2-alkyl-3-(4,5-dihydroisoxazol-3-yl) halobenzenes

A novel process for preparing the compounds of the formula I where: n is 0, 1 or 2; R1,R2 are C1-C6-alkyl; R3,R4,R5 are hydrogen or C1-C6-alkyl, or R4