- PROCESSES FOR THE PREPARATION OF ISOTHIAZOLE DERIVATIVES
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Processes and intermediates for the preparation of compounds of the Formula (1) and the pharmaceutically acceptable salts, prodrugs, solvates and hydrates thereof, wherein R1, R2, and R3 have the definitions provided herei
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Page/Page column 34
(2008/06/13)
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- Dosage forms and methods of treatment using VEGFR inhibitors
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The invention provides dosage forms of a compound of formula 1: or pharmaceutically acceptable salts, solvates or prodrugs thereof. The invention further provides methods of treating hyperproliferative diseases, such as cancers, by administering the dosag
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Page/Page column 6
(2008/06/13)
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- Isothiazole derivatives useful as anticancer agents
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The present invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein X1, R1, R2and R3are as defined herein. The invention also relates to pharmaceutical compositions containing the above compounds and to methods treating hyperproliferative disorders in mammals by administering the above compounds.
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