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M-HYDROXY BENZYL CYANIDE, also known as 2-(3-Hydroxyphenyl)acetonitrile, is an organic compound that serves as an important intermediate in the synthesis of various pharmaceutical compounds. It possesses a hydroxyl group and a nitrile group attached to a benzene ring, which allows for further chemical reactions and modifications.
Used in Pharmaceutical Industry:
M-HYDROXY BENZYL CYANIDE is used as a key intermediate in the synthesis of Pyrrolidine Sulfonamide compounds, which are TRPV4 antagonists. These compounds have potential therapeutic applications in treating various diseases and conditions, such as osteoarthritis, chronic obstructive pulmonary disease (COPD), and atherosclerosis, by modulating the TRPV4 ion channel activity.

25263-44-9

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25263-44-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 25263-44-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,2,6 and 3 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 25263-44:
(7*2)+(6*5)+(5*2)+(4*6)+(3*3)+(2*4)+(1*4)=99
99 % 10 = 9
So 25263-44-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H7NO/c9-5-4-7-2-1-3-8(10)6-7/h1-3,6,10H,4H2

25263-44-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(3-hydroxyphenyl)acetonitrile

1.2 Other means of identification

Product number -
Other names 3-HYDROXYPHENYLACETONITRILE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:25263-44-9 SDS

25263-44-9Relevant articles and documents

TETRAZOLE COMPOUNDS FOR REDUCING URIC ACID

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Paragraph 0103, (2015/11/30)

Uric acid in mammalian subjects is reduced and excretion of uric acid is increased by administering a compound of Formula I. The uric acid-lowering effects of the compounds of this invention are used to treat or prevent a variety of conditions including g

FLUORINATED ARYLALKYLAMINOCARBOXAMIDE DERIVATIVES

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Paragraph 0286; 0287; 0524; 0525, (2014/04/03)

Fluorinated arylalkylaminocarboxamide derivatives of formula (I) are described wherein W, J, n, R1, R2, R3, R4, R5 and R6 have the meanings as defined in the specification and pharmaceutica

FLUORINATED ARYLALKYLAMINOCARBOXAMIDE DERIVATIVES

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Page/Page column 35; 55, (2013/03/26)

Fluorinated arylalkylaminocarboxamide derivatives of formula (I) are described wherein W, J, n, R1, R2, R2', R3, R4, R5 and R6 have the meanings as defined in the specification a

DERIVATIVES OF 4-(2-AMINO-1-HYDROXYETHYL)PHENOL AS AGONISTS OF THE β2 ADRENERGIC RECEPTOR

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Page/Page column 57, (2008/12/05)

The present invention provides a Compound of formula (I), wherein: R1 is a group selected from -CH2OH,-NH(CO)H; and R2 is a hydrogen atom; or R1 together with R2 form the group -NH-C(O)-CH=CH-, wherei

Novel azo dye compound

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Page/Page column 11 - 12, (2008/06/13)

A compound represented by formula (I): Formula (I) wherein Z1 and Z2 each are atoms necessary for forming an aromatic ring; V1 and V2 each are a substituent W1 or W2; when at least one V1 is W1, at least one V2 is W2, or when at least one V1 is W2, at least one V2 is W1; r is 1 to 4; s is 1 to 4; M1 is a counter ion; m1 is the number necessary for neutralizing charge; W1 is a hydroxyl, primary- or secondary- or tertiary-amino, acylamino, or sulfonamido group; W2 is a nitro, cyano, alkoxycarbonyl, aryloxycarbonyl, alkyl- or aryl-sulfonyl, carbamoyl, sulfamoyl, alkenyl, alkynyl, aryl, heterocyclic, sulfo, carboxyl, heterocyclic oxy, ammonio, alkyl- or aryl-sulfinyl, alkyl- or aryl-sulfonyl, acyl, or aryl- or heterocyclic-azo group; and the aromatic ring may have a substituent other than V1 and V2.

ANTITHROMBOTIC AGENTS

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, (2008/06/13)

Compounds of formula (I): Are antithrombotic agents, having utility in a variety of therapeutic areas including the prevention and/or treatment of deep vein thrombosis (DVT) after surgery, major medical illness, paralysis, malignancy, prolonged immobilisa

Antithrombotic agents

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, (2008/06/13)

Compounds of formula (I) : are antithrombotic agents, having utility in a variety of therapeutic areas including the prevention and/or treatment of deep vein thrombosis (DVT) after surgery, major medical illness, paralysis, malignancy, prolonged immobilis

PYRAN DERIVATIVES AND THEIR USE AS INHIBITORS OF 5-LIPOXYGENASE

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, (2008/06/13)

The invention concerns a cyclic ether derivative of the formula I, wherein Ar1 is optionally substituted phenyl, naphthyl or a 9-or 10-membered bicyclic heterocyclic moiety; A1 is a direct link to X1 or (l-3C)alkylene; X1 is oxy, thio, sulphinyl, sulphony

Synthesis of Peptide Alkaloids. 5. New Method for Synthesis of Ansa Peptides. Amino Acids and Peptides. 34

Schmidt, Ulrich,Lieberknecht, Albrecht,Griesser, Helmut,Talbiersky, Jorg

, p. 3261 - 3264 (2007/10/02)

Fourteen-membered para-ansa compounds and 13-membered meta-ansa compounds have been synthesized by catalytic hydrogenation of the pentafluorophenyl esters of ω-(Z)-amino carboxylic acids in 50percent and 80percent yields, respectively.

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