252959-76-5

Basic information

• Product Name: 1,8-Naphthyridine-3-carboxylicacid,2-(trifluoromethyl)-,ethylester(9CI)
• Synonyms: 1,8-Naphthyridine-3-carboxylicacid,2-(trifluoromethyl)-,ethylester(9CI);3-(Ethoxycarbonyl)-2-(trifluoromethyl)-1,8-naphthyridine
• CAS NO: 252959-76-5
• Molecular Formula: C12H9F3N2O2
• Molecular Weight: 270.21
• Product Categories: NAPHTHYRIDINE
• Mol File: 252959-76-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,8-Naphthyridine-3-carboxylicacid,2-(trifluoromethyl)-,ethylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,8-Naphthyridine-3-carboxylicacid,2-(trifluoromethyl)-,ethylester(9CI)(252959-76-5)
• EPA Substance Registry System: 1,8-Naphthyridine-3-carboxylicacid,2-(trifluoromethyl)-,ethylester(9CI)(252959-76-5)

Safety Data

• Hazardous Substances Data: 252959-76-5(Hazardous Substances Data)

Usage

Uses

Ethyl 2-(trifluoromethyl)-1,8-naphthyridine-3-carboxylate

Upstream product

• 7521-41-7 2-Aminonicotinaldehyde 
• 372-31-6 ethyl 4,4,4-trifluoroacetoacetate 

Relevant articles and documents

Indium(Iii) Chloride as an efficient catalyst for friedlander synthesis 1,8-Naphthyridines under solventfree conditions

InCl3 catalyzed Friedlander condensation of 2-aminonicotinaldehyde 1 with carbonyl compounds containing methylene group 2 has been achieved in solvent-free grinding conditions to give 1,8-naphthyridines 3 in high yields. The method is simple an

ZrOClinf2/inf.8Hinf2/infO catalyzed solvent-free Friedlander synthesis of 1,8-naphthyridines

ZrOClinf2/inf.8Hinf2/infO catalyzed Friedlander condensation of 2-Aminonicotinaldehyde 1 with carbonyl compounds containing-methylene group 2 has been achieved in solvent-free grinding conditions to give 1,8-naphthyridines 3. The yields are very good and

Cecl3.7H2O catalyzed Friedlander synthesis of 1,8-naphthyridines under solvent-free grinding conditions

CeCl3.7H2O catalyses the Friedlander condensation of 2-aminonicotinaldehyde 1 with varius carbonyl compounds containing α-methylene group 2 in solvent-free grinding conditions to afford the corresponding 1,8-naphthyridines 3. The rea

Green approach for the efficient synthesis of 1,8-naphthyridines promoted by citric acid

Citric acid catalyzed Friedlander condensation of 2-aminonicotinaldehyde 1 with various carbonyl compounds containing α-methylene group 2 has been achieved under neat conditions at 100° to give the corresponding 1,8-naphthyridines 3. The products are obta

A simple and efficient protocol for the synthesis of 1,8- naphthyridines using sodium hydrogensulfate on silica gel under solvent free condition

A simple and efficient method for the synthesis of 1,8-naphthyridines using silicagel supported sodium hydrogen sulfate as reusable eco-friendly catalyst via Friedlander annulation under solvent-free conditions is described. A series of functionalized der

Potassium triiodide catalyzed Friedlander synthesis of 1,8-naphthyridines in aqueous media

Potassium triiodide catalyses the Friedlander condensation of 2-aminonicotinaldehyde 1 with carbonyl compounds containing α-methylene group 2 in aqueous media to afford 1,-naphthyridines 3 in high yields.

HERBICIDAL COUMPOUNDS

The present invention relates to novel herbicidal [l,8]-naphthyridines of Formula (Ia) or (Ib), or an agronomically acceptable salt of said compound wherein R2, R3, R4, R5,R6,R7, R8, n, m, X and Q are as defined herein. The invention further relates to processes and intermediates for the preparation of the [l,8]-naphthyridines, to compositions which comprise the herbicidal compounds, and to their use for controlling weeds, in particular in crops of useful plants.

Microwave-assisted solvent-free Friedlander synthesis of 1,8-naphthyridines using ammonium acetate as catalyst

The microwave enhanced synthesis of 1,8-naphthyridines 3 is achieved rapidly and in good yield via the Friedlander condensation of 2-aminonicotinaldehyde 1 with carbonyl compounds containing α-methylene group 2 in the presence of ammonium acetate.

Microwave induced Friedlander condensation - A facile synthesis of 1,8-naphthyridines

A simple and efficient method has been developed for the rapid synthesis of 1,8-naphthyridines 3 from 2-aminonicotinaldehyde 1 and active methylene compounds 2 in methanol in the presence of a catalytic amount of piperidine in unmodified domestic microwav

Synthesis of 1,8-naphthyridines under solvent free conditions

Various active methylene compounds 2 reacts efficiently with 2-aminonicotinaldehyde 1 in the presence of piperidine at room temperature within a few minutes and furnish the corresponding 1,8-naphthyridines 3 in high yield under solvent free conditions.