256376-59-7

Basic information

• Product Name: 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid ethyl ester
• Synonyms: 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid ethyl ester;Ethyl 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylate
• CAS NO: 256376-59-7
• Molecular Formula: C₁₆H₁₄FN₃O₂
• Molecular Weight: 299.2996632
• EINECS: -0
• Mol File: 256376-59-7.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator
• Solubility: DMSO (Slightly), Methanol (Very Silghtly)
• CAS DataBase Reference: 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid ethyl ester(256376-59-7)
• EPA Substance Registry System: 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid ethyl ester(256376-59-7)

Safety Data

• Hazardous Substances Data: 256376-59-7(Hazardous Substances Data)

Usage

Uses

1. Used in Pharmaceutical Research:
1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid ethyl ester is used as a stimulator of soluble guanylate cyclase for the development of novel therapeutic agents. Soluble guanylate cyclase is an enzyme that plays a crucial role in the regulation of vascular tone, blood flow, and blood pressure. By stimulating this enzyme, the compound may have potential applications in the treatment of various cardiovascular diseases and conditions related to nitric oxide signaling.
2. Used in Chemical Synthesis:
1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid ethyl ester can also be utilized as an intermediate or building block in the synthesis of more complex molecules with potential pharmaceutical or chemical applications. Its unique structure and functional groups make it a valuable candidate for further modification and development of new compounds with specific properties and activities.
3. Used in Academic Research:
1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid ethyl ester serves as a subject of interest in academic research, where scientists investigate its chemical properties, reactivity, and potential interactions with biological targets. This research can contribute to the understanding of the compound's mechanisms of action and its potential applications in various fields, including drug discovery and development.

Upstream product

• 256504-39-9 ethyl 5-amino-1-(2-fluorobenzyl)-1H-pyrazole-3-carboxylate 
• 927-63-9 3-dimethylaminoacrolein 
• 51859-98-4 (2-fluorobenzyl)hydrazine 
• 927-63-9 (E)-3-(dimethylamino)acrolein 
• 2680-03-7 N,N-Dimethylacrylamide 
• 345-35-7 2-fluorobenzyl chloride 
• 1216246-45-5 (2-fluorobenzyl)hydrazine hydrochloride salt 
• 102-52-3 malonaldehydebis(dimethylacetal) 

Downstream Products

• 256376-62-2 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide 
• 956011-44-2 5-[1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-2-(2,2,2-trifluoroethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 956011-31-7 2-Ethyl-5-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 956011-30-6 5-[1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-2-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 956011-38-4 3-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-1H-1,2,4-triazol-5(4H)-one 
• 956011-29-3 5-[1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-1,3,4-oxadiazol-2(3H)-one 
• 956011-07-7 4-(2,4-Dimethoxybenzyl)-5-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-2-(2,2,2-trifluoroethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 956010-93-8 4-(2,4-dimethoxybenzyl)-2-ethyl-5-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 956010-92-7 4-(2,4-dimethoxybenzyl)-5-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-2-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 956010-91-6 4-(2,4-dimethoxybenzyl)-5-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 956010-90-5 N-(2,4-Dimethoxybenzyl)-2-{[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]carbonyl}-hydrazinecarboxamide 
• 256376-24-6 5-cyclopropyl-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-4-ylamine 

Relevant articles and documents

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