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260550-89-8

(2R)-1-(1-Benzofuran-2-yl)-N-propylpentan-2-amine, commonly referred to as 2-BFMPA, is a substituted amphetamine derivative that belongs to the class of psychoactive drugs. It is structurally related to MDMA (ecstasy) and is recognized for its stimulant and entactogenic effects. As a designer drug, 2-BFMPA has been reported to elicit empathogenic effects in animal studies, and due to its potential for abuse and associated risks, it is regulated in some countries. Its psychoactive properties and potential harmfulness have resulted in its classification as a controlled substance in various jurisdictions.

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  • 260550-89-8 Structure

  • Basic information

    1. Product Name: (2R)-1-(1-Benzofuran-2-yl)-N-propylpentan-2-aMine
    2. Synonyms: (2R)-1-(1-Benzofuran-2-yl)-N-propylpentan-2-aMine;(-)-BPAP;(R)-1-(Benzofuran-2-yl)-N-propylpentan-2-amine
    3. CAS NO:260550-89-8
    4. Molecular Formula: C16H23NO
    5. Molecular Weight: 245.35992
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 260550-89-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 344.7±17.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 0.991±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C(protect from light)
    8. Solubility: N/A
    9. PKA: 10.34±0.29(Predicted)
    10. CAS DataBase Reference: (2R)-1-(1-Benzofuran-2-yl)-N-propylpentan-2-aMine(CAS DataBase Reference)
    11. NIST Chemistry Reference: (2R)-1-(1-Benzofuran-2-yl)-N-propylpentan-2-aMine(260550-89-8)
    12. EPA Substance Registry System: (2R)-1-(1-Benzofuran-2-yl)-N-propylpentan-2-aMine(260550-89-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 260550-89-8(Hazardous Substances Data)

260550-89-8 Usage

Uses

Used in Research Applications:
2-BFMPA is utilized as a research chemical for studying the effects of psychoactive substances on the central nervous system. Its structural similarity to MDMA allows scientists to investigate the mechanisms of action and potential therapeutic applications of entactogens.
Used in Pharmaceutical Development:
Although its psychoactive effects and potential for abuse have led to regulatory measures, 2-BFMPA may still hold promise for pharmaceutical development. Researchers may explore its potential in the treatment of certain conditions, provided that safety and efficacy can be established through rigorous clinical trials.
Used in Forensic Toxicology:
As a controlled substance, 2-BFMPA is relevant in forensic toxicology for the identification and analysis of designer drugs in biological samples. This helps in understanding the prevalence of drug abuse and in legal proceedings related to drug-related offenses.
Used in Drug Policy and Regulation:
The classification of 2-BFMPA as a controlled substance in various jurisdictions necessitates its use in the development and enforcement of drug policies and regulations. This aids in monitoring and controlling the distribution and consumption of potentially harmful psychoactive substances.

Check Digit Verification of cas no

The CAS Registry Mumber 260550-89-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,0,5,5 and 0 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 260550-89:
(8*2)+(7*6)+(6*0)+(5*5)+(4*5)+(3*0)+(2*8)+(1*9)=128
128 % 10 = 8
So 260550-89-8 is a valid CAS Registry Number.

260550-89-8Downstream Products

260550-89-8Relevant articles and documents

Enantioselective synthesis and absolute configuration of (-)-1-(benzofuran-2-yl)-2-propylaminopentane, ((-)-BPAP), a highly potent and selective catecholaminergic activity enhancer

Oka, Takahiro,Yasusa, Takuya,Ando, Takashi,Watanabe, Mayumi,Yoneda, Fumio,Ishida, Toshimasa,Knoll, Joseph

, p. 1213 - 1219 (2007/10/03)

Enantioselective synthesis and absolute configuration of (-)-1-(benzofuran-2-yl)-2-propylaminopentane ((-)-BPAP), which is a highly potent and selective catecholaminergic activity enhancer (CAE) substance, are described. The synthetic approach consists of the coupling reaction of benzofuran with (R)-N-tosyl-2-propylazirizine or (R)-N-methoxy-N-methylnorvaliamide, followed by appropriate modifications of the resulting coupling products. As the results, (-)-BPAP turned out to have the R configuration, which was finally confirmed by X-ray crystallographic analysis.

Structure - Activity studies leading to ( - )1-(Benzofuran-2-yl)-2-propylaminopentane, (( - )BPAP), a highly potent, selective enhancer of the impulse propagation mediated release of catecholamines and serotonin in the brain

Yoneda, Fumio,Moto, Toshiaki,Sakae, Masatoshi,Ohde, Hironori,Knoll, Berta,Miklya, Ildiko,Knoll, Joseph

, p. 1197 - 1212 (2007/10/03)

The catecholaminergic and serotoninergic neurons in the brain change their performance according to the physiological need via a catecholaminergic/serotoninergic activity enhancer (CAE/SAE) mechanism. Phenylethylamine (PEA), tyramine and tryptamine are th

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