260786-00-3

Basic information

• Product Name: 1-(7-METHOXY-1-BENZOFURAN-2-YL)-1-ETHANOL
• Synonyms: 1-(7-METHOXY-1-BENZOFURAN-2-YL)ETHANOL;1-(7-METHOXY-1-BENZOFURAN-2-YL)-1-ETHANOL
• CAS NO: 260786-00-3
• Molecular Formula: C11H12O3
• Molecular Weight: 192.21
• Mol File: 260786-00-3.mol

Chemical Properties

• Boiling Point: 313.3±27.0 °C(Predicted)
• Appearance: /
• Density: 1.190±0.06 g/cm3(Predicted)
• PKA: 13.94±0.20(Predicted)
• CAS DataBase Reference: 1-(7-METHOXY-1-BENZOFURAN-2-YL)-1-ETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(7-METHOXY-1-BENZOFURAN-2-YL)-1-ETHANOL(260786-00-3)
• EPA Substance Registry System: 1-(7-METHOXY-1-BENZOFURAN-2-YL)-1-ETHANOL(260786-00-3)

Safety Data

• Hazardous Substances Data: 260786-00-3(Hazardous Substances Data)

Upstream product

• 43071-52-9 2-Acetyl-7-methoxybenzofuran 
• 75-77-4 chloro-trimethyl-silane 
• 148-53-8 3-methoxy-2-hydroxybenzaldehyde 

Relevant articles and documents

Efficient Transfer Hydrogenation of Ketones using Methanol as Liquid Organic Hydrogen Carrier

Herein, we demonstrate an efficient protocol for transfer hydrogenation of ketones using methanol as practical and useful liquid organic hydrogen carrier (LOHC) under Ir(III) catalysis. Various ketones, including electron-rich/electron-poor aromatic ketones, heteroaromatic and aliphatic ketones, have been efficiently reduced into their corresponding alcohols. Chemoselective reduction of ketones was established in the presence of various other reducible functional groups under mild conditions.

Reductive 3-Silylation of Benzofuran Derivatives via Coupling Reaction with Chlorotrialkylsilane

Reductive silylation of benzofurans with an electron-withdrawing group by a magnesium metal and the subsequent oxidative rearomatization by DDQ gave the selective formation of less reported 3-silylated benzofurans in moderate to good yields under mild reaction conditions with wide substituent scope. The silyl group introduced on the five-membered ring by the reductive coupling could survive with no elimination throughout the oxidation process. The silylated heteroaromatic skeleton is useful as an intermediate in organic synthesis, and its practical utility was also demonstrated by several transformation reactions.

Optically active 1-(benzofuran-2-yl)ethanols and ethane-1,2-diols by enantiotopic selective bioreductions

Enantiotopic selective reduction of 1-(benzofuran-2-yl)ethanones 1a-d, 1-(benzofuran-2-yl)-2-hydroxyethanones 4a-c and 2-acetoxy-1-(benzofuran-2-yl)ethanones 3a-c was performed by baker's yeast for preparation of optically active (benzofuran-2-yl)carbinols [(S)-5a-d, (S)-6a-c and (R)-6a-c, enantiomeric excess from 55 to 93% ee].