262853-30-5

Basic information

• Product Name: 1(2H)-Quinolinecarbothioamide,3,4-dihydro-(9CI)
• Synonyms: 1(2H)-Quinolinecarbothioamide,3,4-dihydro-(9CI);Amino-1,2,3,4-tetrahydroquinol-1-ylmethane-1-thione, 98%
• CAS NO: 262853-30-5
• Molecular Formula: C10H12N2S
• Molecular Weight: 192.285
• Product Categories: THIOAMIDE
• Mol File: 262853-30-5.mol

Chemical Properties

• Boiling Point: 328.8°C at 760 mmHg
• Flash Point: 152.7°C
• Appearance: /
• Density: 1.251g/cm³
• Vapor Pressure: 0.000185mmHg at 25°C
• Refractive Index: 1.669
• CAS DataBase Reference: 1(2H)-Quinolinecarbothioamide,3,4-dihydro-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1(2H)-Quinolinecarbothioamide,3,4-dihydro-(9CI)(262853-30-5)
• EPA Substance Registry System: 1(2H)-Quinolinecarbothioamide,3,4-dihydro-(9CI)(262853-30-5)

Safety Data

• Hazardous Substances Data: 262853-30-5(Hazardous Substances Data)

Usage

Uses

Used in Dye Production:
1(2H)-Quinolinecarbothioamide,3,4-dihydro-(9CI) is utilized as a key component in the production of dyes. Its unique chemical properties allow for the creation of a wide range of colors, making it a valuable asset in this industry.
Used in Agrochemicals:
In the agrochemical sector, 1(2H)-Quinolinecarbothioamide,3,4-dihydro-(9CI) serves as an essential intermediate for the synthesis of various compounds. Its role in this industry is crucial for the development of effective and efficient products.
Used in Pharmaceutical Production:
Quinaldine is also employed in the pharmaceutical industry, where it acts as an intermediate in the synthesis of different organic compounds. Its versatility and reactivity contribute to the development of novel drugs and medications.
Used in Rubber Chemicals:
1(2H)-Quinolinecarbothioamide,3,4-dihydro-(9CI) is used as a vital component in the production of rubber chemicals. Its presence enhances the overall quality and performance of rubber products, making it an indispensable part of this industry.
Used in Corrosion Inhibitors:
As a component in corrosion inhibitors, 1(2H)-Quinolinecarbothioamide,3,4-dihydro-(9CI) helps protect materials from the damaging effects of corrosion. Its inclusion in these products extends the lifespan and durability of various structures and equipment.
Used in Antioxidants:
In the realm of antioxidants, quinaldine plays a significant role in preventing the oxidation of materials, thus preserving their quality and integrity. Its application in this field is essential for maintaining the longevity of various products.
Despite its numerous applications, it is crucial to consider the potential hazards associated with 1(2H)-Quinolinecarbothioamide,3,4-dihydro-(9CI) and implement appropriate safety measures to minimize its impact on human health and the environment. Ongoing research aims to further explore its potential uses and safety considerations, ensuring a balanced approach to its implementation in various industries.

InChI:InChI=1/C10H12N2S/c11-10(13)12-7-3-5-8-4-1-2-6-9(8)12/h1-2,4,6H,3,5,7H2,(H2,11,13)

Upstream product

• 2739-17-5 1,2,3,4-tetrahydroquinoline hydrochloride 
• 635-46-1 1,2,3,4-tetrahydroisoquinoline 
• 333-20-0 potassium thioacyanate 

Downstream Products

• 98347-17-2 benzoyl-(5,6-dihydro-4H-thiazolo[5,4,3-ij]quinolin-2-ylidene)-thiourea 

Relevant articles and documents

Novel inhibitors of nicotinamide-n-methyltransferase for the treatment of metabolic disorders

Nicotinamide-N-methyltransferase (NNMT) is a cytosolic enzyme catalyzing the transfer of a methyl group from S-adenosyl-methionine (SAM) to nicotinamide (Nam). It is expressed in many tissues including the liver, adipose tissue, and skeletal muscle. Its expression in several cancer cell lines has been widely discussed in the literature, and recent work established a link between NNMT expression and metabolic diseases. Here we describe our approach to identify potent small molecule inhibitors of NNMT featuring different binding modes as elucidated by X-ray crystallographic studies.