- A O-trifluoro methyl process for the preparation of formaldehyde
-
The invention discloses a method for preparing o-trifluoromethyl benzaldehyde. The method for preparing the o-trifluoromethyl benzaldehyde, disclosed by the invention, comprises the following steps: in the presence of a catalyst, carrying out hydrolysis reaction on a mixture of o-trifluoromethyl methylbenzene bichloride, o-trifluoromethyl chloro-fluoro-methylbenzene and o-trifluoromethyl methylbenzene difluoride and water at the temperature of 80-150 DEG C to obtain, wherein the mass of the catalyst accounts for 0.01-10% of the mass of the mixture. The method disclosed by the invention is cheap and easily available in raw materials, low in cost, little in wastewater, low in energy consumption and simple in operation and can be suitable for industrial production. The structural formula of the o-trifluoromethyl benzaldehyde is shown in the specification.
- -
-
Paragraph 0036; 0037; 0038
(2017/02/23)
-
- Interactions in molecular crystals, 143 [1]. Ortho-benzene derivatives with meshed cogwheel chloromethyl and methylamino substituents: Structures and rotation enthalpy hypersurfaces
-
Facets of molecular dynamics in organic compounds such as coupled rotations of adjacent substituents are advantageously discussed based on structural data. Within this context, crystal structures of spatially overcrowded ortho-disubstituted benzene derivatives with chloromethyl or methylamino groups are presented together with semiempirical enthalpy hypersurfaces for the substituent rotation. Both compounds, 1-trichloromethyl-2-dichloromethyl-benzene as well as 1-trimethylammonium-2-dimethylamino-benzene exhibit comparable steric overcrowding and their preferred dynamics are predicted to be dominated by the rotation of the threefold substituted group during an approximate standstill of the twofold substituted, mirror-symmetric one. According to known solid state NMR measurements as well as to atom/atom-potential model calculations for the pentachloro ortho-xylene derivative, this molecular dynamic mode is still active in the crystal.
- Bock, Hans,Nagel, Norbert
-
p. 792 - 804
(2007/10/03)
-