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3-Amino-6-mercaptopyridine, also known as 6-Mercapto-3-aminopyridine, is a versatile chemical compound with the molecular formula C5H6N2S. It is a derivative of pyridine, featuring an amino group and a thiol group, which makes it a valuable building block in organic synthesis. 3-Amino-6-mercaptopyridine is recognized for its broad applications across various industries, including pharmaceuticals, dyes, and fine chemicals, as well as its potential in medical research for the development of new therapeutic agents.

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  • 27885-56-9 Structure
  • Basic information

    1. Product Name: 3-Amino-6-mercaptopyridine
    2. Synonyms: 3-Amino-6-mercaptopyridine;2(1H)-Pyridinethione,5-amino-(8CI,9CI);5-aminopyridine-2-thiol;5-amino-1H-pyridine-2-thione
    3. CAS NO:27885-56-9
    4. Molecular Formula: C5H6N2S
    5. Molecular Weight: 126.17954
    6. EINECS: N/A
    7. Product Categories: PYRIDINE;API intermediates
    8. Mol File: 27885-56-9.mol
  • Chemical Properties

    1. Melting Point: 170-171 °C
    2. Boiling Point: 193.6±43.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.31±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 9.15±0.40(Predicted)
    10. CAS DataBase Reference: 3-Amino-6-mercaptopyridine(CAS DataBase Reference)
    11. NIST Chemistry Reference: 3-Amino-6-mercaptopyridine(27885-56-9)
    12. EPA Substance Registry System: 3-Amino-6-mercaptopyridine(27885-56-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 27885-56-9(Hazardous Substances Data)

27885-56-9 Usage

Uses

Used in Pharmaceutical Industry:
3-Amino-6-mercaptopyridine is used as a reagent in the production of pharmaceuticals for its ability to facilitate the synthesis of various drug molecules. Its unique chemical structure allows for the creation of new compounds with potential therapeutic properties.
Used in Dye Industry:
In the dye industry, 3-Amino-6-mercaptopyridine is utilized as a precursor for the synthesis of dyes, taking advantage of its reactive groups to produce a range of colorants for different applications.
Used in Fine Chemicals Production:
3-Amino-6-mercaptopyridine serves as a key component in the synthesis of fine chemicals, where its functional groups contribute to the development of specialty chemicals with specific uses in various sectors.
Used in Corrosion Inhibition:
3-Amino-6-mercaptopyridine has been studied for its potential use in corrosion inhibition, where its thiol group may offer protective properties against metal corrosion in industrial settings.
Used in Heterocyclic Compounds Synthesis:
As a precursor, 3-Amino-6-mercaptopyridine is used in the synthesis of heterocyclic compounds, which are important in the development of complex organic molecules with diverse applications in chemistry and biology.
Used in Medical Research:
In the field of medical research, 3-Amino-6-mercaptopyridine has shown promise in the development of new drugs for the treatment of various diseases, leveraging its chemical properties to target specific biological pathways or mechanisms.

Check Digit Verification of cas no

The CAS Registry Mumber 27885-56-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,8,8 and 5 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 27885-56:
(7*2)+(6*7)+(5*8)+(4*8)+(3*5)+(2*5)+(1*6)=159
159 % 10 = 9
So 27885-56-9 is a valid CAS Registry Number.

27885-56-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-amino-1H-pyridine-2-thione

1.2 Other means of identification

Product number -
Other names 5-Amino-2-pyridinethiol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:27885-56-9 SDS

27885-56-9Downstream Products

27885-56-9Relevant articles and documents

The reduction of specific disulfides with titanium(III) chloride

Akers, Hugh A.,Vang, Meng C.,Updike, Tracie D.

, p. 1364 - 1366 (2007/10/02)

The reaction between titanium(III) chloride and disulfides was investigated.Aryl and alkyl disulfides did not react while heterocyclic aromatic disulfides with a nitrogen α to the sulfur were reduced to the corresponding thiols.Products were identified and characterized by nuclear magnetic resonance and inrared spectra; and melting point comparisons with authentic compounds.The reductions occurred only in the presence of citrate and were found to require 2 moles of titanium(III) per mole of disulfide.

Studies of thiaheterocyclic derivatives. I. Synthesis and pharmacological screening

Delarge,Thunus,Beckers,et al.

, p. 559 - 565 (2007/10/02)

The synthesis of several sulfured heterocyclic compounds has been carried out. They were examined for their antithyroid activity by preliminary screening in rats. The most interesting products are 1-methylimidazolylpyrimidylsulfides. They do not appear as 'pro drugs' of MMI.

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