285124-45-0Relevant articles and documents
A practical synthesis of N-alkyl- and N,N′-dialkyl-polyamines This work is dedicated to the memory of our dear colleague and friend Mr. Charles Edward Price
Haussener, Travis J.,Sebahar, Paul R.,Kanna Reddy, Hariprasada R.,Williams, Dustin L.,Looper, Ryan E.
supporting information, p. 2845 - 2848 (2016/06/14)
A variety of polyamines have been synthesized from their corresponding amino alcohols through a 3-step process. The synthesis predicates that the most likely impurities are of higher molecular weight and that distillation is effective at producing highly pure materials. This sequence is scalable, requires no protecting groups or chromatography, and provides the requisite polyamines in moderate to good yields.
METHOD OF PRODUCING N-ALKYL POLYAMINES
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Page/Page column 20, (2016/03/22)
In one embodiment, the invention presents a process for the preparation of N-alkyl polyamines that includes (i) the conversion of an amino alcohol to an aminoalkyl alkylating agent with a halo or aldehyde reactive group and (ii) the addition of amines to an aminecontaining alkylating agent to make an N-alkyl polyamine.
Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents
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Page column 44, (2010/02/05)
This invention relates to 2-arylimino heterocycles, including 2-arylimino-1,3-thiazolidines, 2-arylimino-2,3,4,5-tetrahydro-1,3-thiazines, 2-arylimino-1,3-thiazolidin-4-ones, 2-arylimino-1,3-thiazolidin-5-ones, and 2-arylimino-1,3-oxazolidines, and their use in modulating progesterone receptor mediated processes, and pharmaceutical compositions for use in such therapies.
