28569-88-2

Basic information

• Product Name: Ethyl 2-hydroxy-2,2-di(thiophen-2-yl)acetate
• Synonyms: Ethyl 2-hydroxy-2,2-di(thiophen-2-yl)acetate;Hydroxydithiophen-2-ylacetic acid ethyl ester;Aclidinium Impurity 4
• CAS NO: 28569-88-2
• Molecular Formula: C₁₂H₁₂O₃S₂
• Molecular Weight: 268.35188
• Mol File: 28569-88-2.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: Ethyl 2-hydroxy-2,2-di(thiophen-2-yl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 2-hydroxy-2,2-di(thiophen-2-yl)acetate(28569-88-2)
• EPA Substance Registry System: Ethyl 2-hydroxy-2,2-di(thiophen-2-yl)acetate(28569-88-2)

Safety Data

• Hazardous Substances Data: 28569-88-2(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
Ethyl 2-hydroxy-2,2-di(thiophen-2-yl)acetate is used as an intermediate in the synthesis of various organic compounds. Its unique structure allows it to be a valuable building block for the creation of new molecules with specific properties and functions.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Ethyl 2-hydroxy-2,2-di(thiophen-2-yl)acetate is used as a key component in the development of new drugs. Its thiophene ring can be modified to create novel drug candidates with potential therapeutic applications.
Used in Material Science:
Ethyl 2-hydroxy-2,2-di(thiophen-2-yl)acetate is also used in the field of material science, where it can be employed to develop new materials with specific properties. For example, it can be used to create conductive polymers or other materials with unique electronic, optical, or mechanical properties.
Used in Dye and Pigment Industry:
Due to its thiophene structure, Ethyl 2-hydroxy-2,2-di(thiophen-2-yl)acetate can be used in the dye and pigment industry to create new colorants with specific shades and properties. Its ability to absorb and emit light in the visible region makes it a potential candidate for the development of new dyes and pigments.

Upstream product

• 89180-57-4 2-thienylmagnesium iodide 
• 4075-58-5 thienylglycoxylate dethyle 
• 2786-07-4 2-thienyl lithium 
• 5713-61-1 thiophen-2-yl magnesium bromide 

Downstream Products

• 78196-89-1 (5-Phenyl-2-thienyl)(2-thienyl)acetic acid 
• 925700-76-1 anti-(1S,2R)-hydroxy-di-thiophen-2-yl-acetic acid (1S,2R)-7-(benzylmethylamino)-bicyclo[2.2.1]hept-2-yl ester 
• 320347-97-5 hydroxydithien-2-ylacetic acid 1-aza-bicyclo[2.2.2]oct-3(R)-yl ester 
• 1195981-90-8 (R)-3-(2-hydroxy-2,2-dithiophen-2-yl-acetoxy)-1-(5-phenylisoxazol-3-ylmethyl)-1-azoniabicyclo[2.2.2]octane chloride 
• 4746-63-8 2-hydroxy-2,2-di(thiophen-2-yl)acetic acid 

Relevant articles and documents

QUINUCLIDINE DERIVATIVES AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS

The invention provides compounds of formula (I) wherein R1, R2, R3, Het1, n, Y and X are as defined in the specification, a process for their preparation, pharmaceutical compositions containing them, a process f

A Study of Some Thiophene Analogues of Glycolic Acid

Reaction of phenyl(3-thienyl)glycolic acid (1) with AlCl3 in benzene solution leads to the formation of 4H-indenothiophene-4-carboxylic acid (2) whereas analogous reaction of phenyl(2-thienyl)glycolic acid (4) produces no indenothiophene but only a mixture of 5 and 6.In the case of di-(2-thienyl)glycolic acid (14b) and di-(3-thienyl)glycolic acid (16b) analogous results are obtained, with the former leading to the formation of 15 and the latter producing 17.In the case of the (benzothienyl)phenylglycolic analogues of 1 and 4 the acids were unstable to heat so that the esters, ethyl (2-benzothienyl)phenylglycolate (21) and ethyl (3-benzothienyl)phenylglycolate (20), upon treatment with AlCl3 in benzene led to cyclized products only.The former gave 23 which was saponified and decarboxylated to yield 25 and compared with an authentic sample obtained by synthesis.Ester 20 similarly gave 22 which was similarly converted to the known 24.A mechanistic explanation of these findings is proposed.