286369-94-6

Basic information

• Product Name: N-{4-[(6,7-Dimethoxy-4-quinolyl)oxy]-2,5-dimethylphenyl}-N'-(3-fluoro-2-methoxyphenyl)urea
• Synonyms: N-{4-[(6,7-Dimethoxy-4-quinolyl)oxy]-2,5-dimethylphenyl}-N'-(3-fluoro-2-methoxyphenyl)urea
• CAS NO: 286369-94-6
• Molecular Weight: 491.519
• Mol File: 286369-94-6.mol

Chemical Properties

• CAS DataBase Reference: N-{4-[(6,7-Dimethoxy-4-quinolyl)oxy]-2,5-dimethylphenyl}-N'-(3-fluoro-2-methoxyphenyl)urea(CAS DataBase Reference)
• NIST Chemistry Reference: N-{4-[(6,7-Dimethoxy-4-quinolyl)oxy]-2,5-dimethylphenyl}-N'-(3-fluoro-2-methoxyphenyl)urea(286369-94-6)
• EPA Substance Registry System: N-{4-[(6,7-Dimethoxy-4-quinolyl)oxy]-2,5-dimethylphenyl}-N'-(3-fluoro-2-methoxyphenyl)urea(286369-94-6)

Safety Data

• Hazardous Substances Data: 286369-94-6(Hazardous Substances Data)

Upstream product

• 286371-46-8 4-[(6,7-dimethoxy-4-quinolyl)oxy]-2,5-dimethylaniline 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 437-83-2 3-fluoro-2-methoxyaniline 
• 144-55-8 sodium hydrogencarbonate 

Relevant articles and documents

QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES

An object of the present invention is to provide compounds which have antitumor activity and do not change cytomorphosis. Disclosed are compounds represented by formula (I) and a pharmaceutically acceptable salts and solvates thereof and pharmaceutical compositions comprising said compounds: wherein X and Z each independently represent CH or N; R1 to R3 represent H, substituted alkoxy, unsubstituted alkoxy or the like; R4 represents H; R5 to R8 represent H, halogen, alkyl, alkoxy, alkylthio, nitro, or amino, provided that R5 to R8 do not simultaneously represent H; R9 and R10 represent H, alkyl, or alkylcarbonyl; and R11 represents alkyl, alkenyl, alkynyl, or aralkyl.