289038-22-8

Basic information

• Product Name: 5-BROMO-4-CHLORO-2-FLUOROBENZOIC ACID
• Synonyms: 5-BROMO-4-CHLORO-2-FLUOROBENZOIC ACID;Benzoic acid, 5-broMo-4-chloro-2-fluoro-;5-bromo-2-fluoro-4-Chlorobenzoic acid
• CAS NO: 289038-22-8
• Molecular Formula: C₇H₃BrClFO₂
• Molecular Weight: 253.45
• Product Categories: blocks;Bromides;Carboxes;Benzoic acid;Acids & Esters;Bromine Compounds;Chlorine Compounds;Fluorine Compounds
• Mol File: 289038-22-8.mol

Chemical Properties

• Boiling Point: 329.1 °C at 760 mmHg
• Flash Point: 152.8 °C
• Appearance: /
• Density: 1.887 g/cm³
• Vapor Pressure: 7.31E-05mmHg at 25°C
• Refractive Index: 1.597
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.65±0.10(Predicted)
• CAS DataBase Reference: 5-BROMO-4-CHLORO-2-FLUOROBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-4-CHLORO-2-FLUOROBENZOIC ACID(289038-22-8)
• EPA Substance Registry System: 5-BROMO-4-CHLORO-2-FLUOROBENZOIC ACID(289038-22-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 289038-22-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-Bromo-4-chloro-2-fluorobenzoic acid is used as an intermediate in the synthesis of various pharmaceutical products for its unique chemical properties and potential biological activities. Its presence in the molecular structure of certain drugs can enhance their therapeutic effects and pharmacological properties.
Used in Agrochemical Industry:
In the agrochemical industry, 5-Bromo-4-chloro-2-fluorobenzoic acid is utilized as a key component in the development of agrochemicals, such as pesticides and herbicides. Its chemical structure allows for the creation of compounds with specific target sites in pests or weeds, improving the effectiveness and selectivity of these products.
Used in Dye Production:
5-Bromo-4-chloro-2-fluorobenzoic acid is used as a starting material in the production of dyes due to its ability to form colored compounds. Its unique chemical structure contributes to the color intensity and stability of the resulting dyes, making it suitable for various applications, including textiles, plastics, and printing inks.
Used in Polymer Industry:
In the polymer industry, 5-Bromo-4-chloro-2-fluorobenzoic acid is employed as a monomer or a modifier in the synthesis of polymers. Its presence in the polymer chain can impart specific properties, such as flame retardancy, UV resistance, or improved mechanical strength, depending on the desired application.
Used in Chemical Research:
5-Bromo-4-chloro-2-fluorobenzoic acid is used as a research compound in chemical laboratories for studying its reactivity, stability, and potential applications in various chemical reactions. Its unique structure allows researchers to explore new synthetic routes and develop novel compounds with potential industrial or pharmaceutical applications.

InChI:InChI=1/C7H3BrClFO2/c8-4-1-3(7(11)12)6(10)2-5(4)9/h1-2H,(H,11,12)

Upstream product

• 951884-02-9 5-bromo-4-chloro-2-fluoro-benzoic acid methyl ester 
• 716362-14-0 methyl 5-amino-4-chloro-2-fluorobenzoate 
• 1070893-15-0 methyl 4-chloro-2-fluoro-5-nitrobenzoate 
• 35112-05-1 4-chloro-2-fluoro-5-nitro-benzoic acid 

Downstream Products

• 1070892-56-6 5-bromo-4-chloro-2-fluoro-benzoyl chloride 
• 1258214-06-0 C₁₄H₁₄BrClFNO₃ 

Relevant articles and documents

INHIBITORS OF STEAROYL-COA DESATURASE

Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity.

GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO

GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure, wherein R1a, R1b, R1c, R1d, R2, R2a, and A are as defined herein, including stereoisomers, esters, solvates and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.