- Reinvestigation of phase-transfer-catalyzed chlorpyrifos synthesis
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Production of chlorpyrifos via the phase-transfer-catalyzed reaction of 0,0-diethylphosphorochloridothioate and the sodium salt of 3,5,6- trichloropyridin-2-ol was reinvestigated. The formation of sulfotep (the major byproduct) and the yield are influence
- Fakhraian,Moghimi,Ghadiri,Dehnavi,Sadeghi
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- Chlorpyrifos production method
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Provided is a chlorpyrifos production method. Trichloro-acetic chloride is used as a starting raw material, an intermediate 3,3,5,6-tetrachloro-4,5-dihydropyridine-2(3H)-ketone is synthesized throughaddition and cyclization reaction, and then chlorpyrifos is synthesized through alkaline hydrolysis, condensation reaction and one-pot process reaction. The 3,5,6-trichloropyridine-2-sodium phenolatefiltering link after alkaline hydrolysis reaction is omitted, the chlorpyrifos is synthesized through a one-pot process, and operation steps are simplified. A dual-solvent method is adopted for condensation reaction, hydrolysis of O,O-diethyl thiophosphoryl chloride and generation of sulfotep can be effectively inhibited, the content of the synthesized chlorpyrifos product is 97% or above, and thetotal yield is 83% or above. Produced wastewater is greatly decreased, the total wastewater discharging amount is reduced by about 50% compared with an existing process, and the chlorpyrifos production method is suitable for industrial production.
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Paragraph 0033-0050
(2018/05/01)
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- Investigation on the acylation of heterocyclic alcoholate anions with O,O-dialkyl phosphorochloridothioate in water solvent
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The acylation of some heterocyclic alcoholate anions with O,O-dialkyl phosphorochloridothioate has been investigated. Higher yields and fewer byproducts were achieved in water at 50 °C by employing an effective phase-transfer catalyst (PTC) (benzyl triethylammonium chloride [BTEAC]), acylation catalyst (AC) (4-dimethylaminopyridine), and surfactant (sodium dodecyl sulfate), under weakly basic (pH 9.5~10) conditions. This reaction can also be applied to synthesize other insecticides with excellent yields.
- Ge, Xin,Qian, Chao,Chen, Xinzhi
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p. 739 - 744
(2013/07/25)
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- Concentrates of organophosphorous insecticides
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A low volatile organic compound co-solvent system is disclosed for preparing emulsion concentrates of low melting organophosphorous insecticides wherein the bioefficacy of the insecticide active is significantly enhanced. The co-solvent system comprises a water-soluble ethoxylated fatty acid/rosin acid-nonionic surfactant composition.
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- Fungicidal active compound combinations
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The present application relates to new active compound combinations composed, on the one hand, of prior art compounds metaconazole, 5-[(4-chlorophenyl)methyl]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-yl-methyl)cyclopentanol and imidacloprid, 1-[(6-chloro-3-pyridinyl)-methyl]-4,5-dihydro-N-nitro-1H-imidazole-2-amine, and, on the other hand, of other prior-art active compounds, the combinations being extremely suitable for the protection of wood products.
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- Anti-fouling compositions
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An anti-fouling composition comprising a carrier, and a binder, the improvement which comprises an effective amount of at least one insecticide. The composition is applied to the surfaces of articles which come into contact with seawater or brackish water, especially wood. Other conventional anti-fouling agents may also be present.
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- Substituted arylazadioxacyclo alkene fungicides
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The invention relates to novel substituted arylazadioxacycloalkenes, a plurality of processes for their preparation and to their use as fungicides.
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- Pesticidal composition containing a microencapsulated organo-phosphorus or carbamate in a pyrethroid dispersion
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An insecticidal and/or acaricidal and/or nematicidal composition having a rapid efficacy and residual activity which comprises a mixture of a poorly water-soluble organophosphorus insecticide and/or acaricide and/or nematicide and/or a poorly water-soluble carbamate insecticide and/or acaricide which have been microencapsulated in water-insoluble polymer coatings with a dispersing agent used in forming a microcapsule part, with a poorly water-soluble pyrethroid insecticide and/or acaricide emulsified or suspended in water with the above-mentioned dispersing agent used in forming a flowable part.
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- Process for preparing phosphorothioates and phosphonoates in a three-phase system
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The present invention is directed to the preparation of certain phosphorothioates and phosphonoates by means of a process which employs a three-phase system for the reaction of an alkali metal or alkaline earth metal phenate, pyridinate or pyrimidinate with a phosphorochloridothioate or phosphorochloridate under alkaline conditions and in the presence of tertiary amine and quarternary ammonium salt co-catalyst, but in the absence of both a hydrocarbon or chlorinated hydrocarbon solvent and a surfactant.
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- Macrocyclic plant acaricides
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Compounds of the formula I STR1 in which either R is methyl and there is a double bond in the 9,10-position, or in which R is hydrogen and there is a single bond in the 9,10-position, are highly active against Acarina which damage plants.
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- Liquid formulations
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A pour-on formulation comprising one or more ectoparasiticides in a solvent system comprising 80 to 98% w/v of a fixed oil and 2 to 20% w/v of a volatile silicone, a method for its preparations and its use in the control of ectoparasiticides on animals.
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- Process for preparing phosphorothioates and phosphates
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Certain phenyl and N-heterocyclic phosphorothioates and phosphates are prepared by the reaction of an appropriate alkali metal or alkaline earth metal -O-phenyl or N-heterocyclic compound with an appropriate phosphorochloridate or phosphorochloridothioate under alkaline conditions in a liquid reaction medium and in the presence of a tertiary amine catalyst and a nonionic surfactant having a HLB Value of from about 2.5 to about 20 or more.
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- Insecticidal composition for agricultural and horticultural use
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A synergistic insecticidal composition comprising a nitromethylene derivative of the formula STR1 in which X is a lower alkyl group, a lower alkoxy group or a halogen atom, n is 0, 1 or 2, and m is 2 or 3, and an insecticide which is a carboxylic acid ester, carbamate, organophosphate ester or one of a group of specific compounds.
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- Nitro- and cyanoguanidines as selective preemergence herbicides and plant defoliants
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There are provided novel nitroguanidine and cyanoguanidine compounds. A method of dessicating and defoliating plants by applying to the foliage thereof certain nitroguanidine or cyanoguanidine compounds and a method for the selective preemergence control of undesirable broadleaf weeds and grasses in the presence of graminaceous crops are disclosed.
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- Process for preparing phosphorothioates and phenylphosphonothioates
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Mixtures of (1) a quaternary ammonium salt(s) and (2) 1,4-diazabicyclo[2.2.2]octane are novel catalysts in the process of reacting an alkali metal phenate, pyridinate or pyrimidiate with an O,O-dialkyl phosphorochloridothioate or O-alkyl phenylphosphonochloridothioate to produce the corresponding phosphorothioates and phenylphosphonothioates. The process is conducted under alkaline conditions in a liquid reaction medium. As an example, O,O-diethyl 0-(3,5,6-trichloro-2-pyridyl)phosphorothioate is prepared in excellent yields and purity by reacting sodium 3,5,6-trichloropyridinate with O,O-diethyl phosphorochloridothioate in a stirred methylene chloride-water reaction medium in the presence of a catalytic amount of benzyltriethylammonium chloride and 1,4-diazabicyclo[2.2.2]octane.
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- Process for preparing phosphorothioates and phenylphosphonothioates
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Mixtures of (1) a quaternary ammonium salt(s) and (2) a diazole are novel catalysts in the process of reacting an alkali metal phenate, pyridinate or pyrimidinate with an O,O-dialkyl phosphorochloridothioate or O-alkyl phenylphosphonochloridothioate to produce the corresponding title compounds. The process is conducted under alkaline conditions in a liquid reaction medium. As an example, O,O-diethyl O-(3,5,6-trichloro-2-pyridyl)phosphorothioate is prepared in excellent yields and purity by reacting sodium 3,5,6-trichloro-2-pyridinate with O,O-diethyl phosphorochloridothioate in a stirred methylene chloride-water reaction medium in the presence of a catalytic amount of benzyltriethylammonium chloride and 1-methylimidazole.
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- Condensation products
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Formamidine compounds of the formula EQU1 or WHEREIN R1 represents a substituted or unsubstituted phenyl radical, R2 represents hydroogen, alkyl, alkenyl or alkinyl and R3 represents acyl their manufacture and their use in pest control.
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- Process for preparing phosphorothioates and phenylphosponothioates
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Quaternary ammonium salts are novel catalysts in the process of reacting an alkali metal phenate, pyridinate or pyrimidinate with an O,O-dialkyl phosphorochloridothioate or O-alkyl phenylphosphonochloridothioate to produce the corresponding phosphorothioates and phenylphosphonothioates. The process is conducted under alkaline conditions in a liquid reaction medium. As an example, O,O-diethyl O-(3,5,6-trichloro-2-pyridyl)-phosphorothioate is prepared in excellent yields and purity by reacting solid particulate sodium 3,5,6-trichloropyridinate with O,O-diethyl phosphorochloridothioate dissolved in a stirred methylene chloride reaction medium in the presence of a catalytic amount of benzyltriethylammonium chloride.
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