304902-95-2

Basic information

• Product Name: 5-BROMO-2-CYCLOPROPYLPYRIMIDINE-4-CARBOXYLIC ACID
• Synonyms: 5-BROMO-2-CYCLOPROPYLPYRIMIDINE-4-CARBOXYLIC ACID;5-bromo-2-cyclopropyl-4-Pyrimidinecarboxylic acid
• CAS NO: 304902-95-2
• Molecular Formula: C8H7BrN2O2
• Molecular Weight: 243.05738
• Mol File: 304902-95-2.mol

Chemical Properties

• Boiling Point: 385.3±27.0 °C(Predicted)
• Appearance: /
• Density: 1.833±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 1.53±0.10(Predicted)
• CAS DataBase Reference: 5-BROMO-2-CYCLOPROPYLPYRIMIDINE-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2-CYCLOPROPYLPYRIMIDINE-4-CARBOXYLIC ACID(304902-95-2)
• EPA Substance Registry System: 5-BROMO-2-CYCLOPROPYLPYRIMIDINE-4-CARBOXYLIC ACID(304902-95-2)

Safety Data

• Hazardous Substances Data: 304902-95-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Drug Development:
5-BROMO-2-CYCLOPROPYLPYRIMIDINE-4-CARBOXYLIC ACID is used as a key intermediate in the synthesis of various pharmaceutical compounds due to its unique structural features and potential biological activities. Its cyclopropyl substituent and carboxylic acid group enable the development of new drugs with improved efficacy and selectivity.
Used in Agrochemical Compounds Synthesis:
In the agrochemical industry, 5-BROMO-2-CYCLOPROPYLPYRIMIDINE-4-CARBOXYLIC ACID is utilized as a building block for the synthesis of agrochemical compounds, such as insecticides and herbicides. Its structural features and functional groups can be exploited to create novel agrochemicals with enhanced performance and selectivity.
Used in Medicinal Chemistry:
5-BROMO-2-CYCLOPROPYLPYRIMIDINE-4-CARBOXYLIC ACID is employed as a target for further investigation in medicinal chemistry. Its bromo and carboxylic acid functional groups may impart specific pharmacological properties, making it a promising candidate for the development of new therapeutic agents with novel mechanisms of action.
Used in Drug Design and Optimization:
5-BROMO-2-CYCLOPROPYLPYRIMIDINE-4-CARBOXYLIC ACID serves as a valuable starting point for drug design and optimization efforts. Its unique structural features can be modified and fine-tuned to improve the potency, selectivity, and pharmacokinetic properties of drug candidates, leading to the development of more effective and safer medications.
Used in Chemical Synthesis and Organic Chemistry:
Beyond its applications in the pharmaceutical and agrochemical industries, 5-BROMO-2-CYCLOPROPYLPYRIMIDINE-4-CARBOXYLIC ACID is also used as a versatile building block in chemical synthesis and organic chemistry. Its reactivity and functional groups can be exploited in various synthetic routes and reactions, enabling the preparation of a wide range of organic compounds with diverse applications.

Upstream product

• 766-38-1 mucobromic acid 
• 477904-80-6 cyclopropanecarboximidamidine hydrochloride 
• 21577-50-4 mucobromic acid 
• 57297-29-7 cyclopropylcarboxamidine hydrochloride 

Downstream Products

• 304902-96-3 5-bromo-2-cyclopropyl-pyrimidine 

Relevant articles and documents

HERBICIDAL PYRIMIDINE COMPOUNDS

The present invention relates to the pyrimidine compounds of formula (I), or their agriculturally acceptable salts or derivatives as herbicides, wherein the variables are defined according to the description, use of pyrimidine compounds of formula (I) as herbicides, compositions comprising them and their use as herbicides, i.e. for controlling harmful plants, and also a method for controlling unwanted vegetation which comprises allowing a herbicidal effective amount of at least one pyrimidine compound of the formula (I) to act on plants, their seed and/or their habitat.

HERBICIDAL PYRIMIDINE COMPOUNDS

The present invention relates to the pyrimidine compounds of formula (I), or their agriculturally acceptable salts or derivatives as herbicides, wherein the variables are defined according to the description, use of pyrimidine compounds of formula (I) as herbicide, compositions comprising them and their use as herbicides, i.e. for controlling harmful plants, and also a method for controlling unwanted vegetation which comprises allowing a herbicidal effective amount of at least one pyrimidine compounds of the formula (I) to act on plants, their seed and/or their habitat.

HERBICIDAL PYRIMIDINE COMPOUNDS

The present invention relates to the compounds of formula (I), or their agriculturally acceptable salts or derivatives as herbicides, wherein the variables are defined according to the description, use of compounds of formula (I) as herbicides, compositio

HERBICIDAL PYRIMIDINE COMPOUNDS

The present invention relates to the pyrimidine compounds of formula (I), or their agriculturally acceptable salts or derivatives as herbicides, wherein the variables are defined according to the description, use of pyrimidine compounds of formula (I) as herbicide, compositions comprising them and their use as herbicides, i.e. for controlling harmful plants, and also a method for controlling unwanted vegetation which comprises allowing a herbicidal effective amount of at least one pyrimidine compounds of the formula (I) to act on plants, their seed and/or their habitat.

NOVEL HYDANTOIN DERIVATIVES FOR THE TREATMENT OF OBSTRUCTIVE AIRWAY DISEASES

The invention provides compounds of formula (I), wherein R1 and R2 are as defined in the specification; processes for their preparation; pharmaceutical compositions containing them; a process for preparing the pharmaceutical compositions; and their use in therapy.