57297-29-7

Basic information

• Product Name: Cyclopropane-1-carboximidamide hydrochloride
• Synonyms: CYCLOPROPYL CARBAMIDINE HCL;CYCLOPROPYLCARBAMIDINE HYDROCHLORIDE;CYCLOPROPANECARBOXAMIDINE HYDROCHLORIDE;CYCLOPROPANECARBOXIMIDAMIDE HYDROCHLORIDE;CYCLOPROPANE-1-CARBOXIMIDAMIDE HYDROCHLORIDE;BUTTPARK 43\57-26;Clcyopropylcarbamidinehydrochloride;Cyclopropylcarbamidinehydrochloride,97%
• CAS NO: 57297-29-7
• Molecular Formula: C₄H₈N₂*ClH
• Molecular Weight: 120.58
• EINECS: -0
• Product Categories: Ring Systems;Cycloalkanes
• Mol File: 57297-29-7.mol
• Article Data: 8

Chemical Properties

• Melting Point: 123 °C
• Boiling Point: 133.6 °C at 760 mmHg
• Flash Point: 34.6 °C
• Appearance: white to light yellow crystal powder
• Density: 1.37g/cm3
• Vapor Pressure: 8.42mmHg at 25°C
• Storage Temp.: Inert atmosphere,Room Temperature
• Water Solubility: Soluble in water
• Sensitive: Hygroscopic
• BRN: 4507255
• CAS DataBase Reference: Cyclopropane-1-carboximidamide hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopropane-1-carboximidamide hydrochloride(57297-29-7)
• EPA Substance Registry System: Cyclopropane-1-carboximidamide hydrochloride(57297-29-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-37/39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 57297-29-7(Hazardous Substances Data)

Usage

Chemical Properties

white to light yellow crystal powde

InChI:InChI=1/C4H8N2/c5-4(6)3-1-2-3/h3H,1-2H2,(H3,5,6)/p+1

Upstream product

• 5500-21-0 cyclopropropanecarbonitrile 
• 63190-44-3 cyclopropanecarboximidic Acid Ethyl Ester Hydrochloride 

Downstream Products

• 911635-51-3 t-butyl 2-cyclopropyl-4-(trifluoromethyl)-5,8-dihydropyrido[3,4-d]pyrimidine-7(6H)-carboxylate 
• 1192469-32-1 3-(4-chlorophenyl)-5-cyclopropyl-1H-1,2,4-triazole 
• 459796-19-1 2-cyclopropylquinazolin-4(3H)-one 
• 221548-37-4 2-cyclopropyl-5-methyl-1H-benzimidazole 
• 16405-79-1 2-cyclopropyl-1H-benzo[d]imidazole 
• 866602-89-3 5-(benzyloxy)-2-cyclopropylpyrimidine 
• 1023953-54-9 C₁₅H₂₁N₃O₃ 
• 945955-11-3 2-cyclopropyl-6-isobutylpyrimidine-4-ol 
• 945002-67-5 6-(3,4-dichlorophenyl)-2-cyclopropyl-4-hydroxypyrimidine-5-carbonitrile 
• 304902-95-2 5-bromo-2-cyclopropyl-pyrimidine-4-carboxylic acid 
• 927430-65-7 6-amino-7-chloro-2-cyclopropyl-1-methyl-1H-benzoimidazole-5-carboxylic acid methyl ester 
• 7043-10-9 2-cyclopropyl-6-methyl-4-hydroxy-pyrimidine 
• 54070-74-5 cyclopropanecarboxamidine 
• 265324-26-3 2-cyclopropylpyrimidin-4-amine 

Relevant articles and documents

Discovery of the bifunctional modulator of angiotensin II type 1 receptor (AT1R) and PPARγ derived from the AT1R antagonist, Fimasartan

Inspired by the well-known PPARγ partial agonism of angiotensin II type 1 receptor (AT1R) antagonists exemplified by an antihypertensive drug, Telmisartan, efforts to identify compounds with the dual activities have been pursued in order to control the two major metabolic disorders, hypertension and hyperglycemia simultaneously. Lead compound 18 derived from the AT1R antagonist, Fimasartan, has successfully presented the possibility to control the medical conditions by a single molecule.

PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES

The present invention relates to substituted pyrimidine derivatives, as well as N- oxides thereof and agriculturally acceptable salts thereof, and their use to control undesired plant growth, in particular in crops of useful plants. The invention extends to herbicidal compositions comprising such compounds, N-oxides and/or salts as well as mixtures of the same with one or more further active ingredient (such as, for example, an herbicide, fungicide, insecticide and/or plant growth regulator) and/or a safener. The invention further relates to intermediates useful in the preparation of such compounds, and to processes for their preparation.

METHOD FOR PREPARING SUBSTITUTED PYRIMIDINES

Disclosed a method for preparing a ester (Formula I) wherein R1 is cyclopropyl, 4-chlorophenyl or 4-bromophenyl; and R2 is C1-C14 alkyl; comprising contacting acetal (Formula II) with a persulfate oxidant in the presence of a strong sulfur- or phosphorus-containing mineral acid and an oxidation resistant solvent.