308289-58-9

Basic information

• Product Name: 4-(bicyclo[2.2.1]hept-2-yloxy)-4-oxobutanoic acid
• Synonyms: 4-(bicyclo[2.2.1]hept-2-yloxy)-4-oxobutanoic acid
• CAS NO: 308289-58-9
• Molecular Formula: C11H16O4
• Molecular Weight: 212.24234
• Mol File: 308289-58-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(bicyclo[2.2.1]hept-2-yloxy)-4-oxobutanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(bicyclo[2.2.1]hept-2-yloxy)-4-oxobutanoic acid(308289-58-9)
• EPA Substance Registry System: 4-(bicyclo[2.2.1]hept-2-yloxy)-4-oxobutanoic acid(308289-58-9)

Safety Data

• Hazardous Substances Data: 308289-58-9(Hazardous Substances Data)

Upstream product

• 498-66-8 norborn-2-ene 
• 110-15-6 succinic acid 
• 108-30-5 succinic acid anhydride 
• 497-37-0 exo-2-norbornanol 
• 497-36-9 (+/-)-endo-2-norborneol 

Downstream Products

• 497-36-9 (+/-)-endo-2-norborneol 

Relevant articles and documents

Synthesis of bi-and tricyclic monoesters of dicarboxylic acids

A thermal addition of aliphatic dicarboxylic acids to bicyclo[2.2.1]- heptene hydrocarbons and to tricyclo[5.2.1.02,6]deca-3,8-diene was investigated and new samples of dicarboxylic acids alicyclic monoesters were synthesized. Some of monoesters synthesized have a pleasant fragrance and can find application as fragrance substances. They are also of interest as initial components for preparation of new organic compounds. Nauka/Interperiodica 2006.

Cooling Compounds

A cooling composition comprising at least one compound of the Formula I in which R is selected from the group of moieties consisting of (CH2)nCOOR″; (CH2)nCONMe2; (CH2)nOR″; and CHNH2CH3; where n is 1-3 and R″ is independently selected from hydrogen, methyl and ethyl; and R′ is selected from the group consisting of the moieties fenchyl, D-bornyl, L-bornyl, exo-norbornyl, 2-methylisobornyl, 2-ethylfenchyl, 2-methylbornyl, cis-pinan-2-yl, verbanyl and isobornyl. The compositions are useful in providing cooling sensations to the skin or mucous membranes of the body.

Convenient Synthesis of Alcohol O-Hemiesters using Isopropenyl Esters as Acylating Reagents: Synthesis of Hydrophilic Oxaunomycin 10-O-Hemiester Derivatives

Various types of alcohol O-hemiesters 7a-m were synthesized conveniently in good yield by reaction with isopropenyl esters 4a-f in the presence of a catalytic amount of conc.H2SO4 or toluene-p-sulfonic acid followed by selective deprotection of the terminal esters.This method was applied to a preparation of hydrophilic oxaunomycin 10-O-hemiester derivatives 14a,b and 19a-c.