cas 309757-71-9, (S)-3-(3'-FLUOROPHENYL)ALANINE T-BUTYL ESTER | Articles data ｜lookchem

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309757-71-9

Articles about 309757-71-9Total 4 be found

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BICYCLIC-PYRIMIDINEDIONE COMPOUNDS
The present invention provides novel bicyclic pyrimidinedione compounds that are useful for the treatment of hypertrophic cardiomyopathy (HCM) and conditions associated with left ventricular hypertrophy or diastolic dysfunction. The synthesis and characterization of the compounds is described, as well as methods for treating HCM and other forms of heart disease.
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Paragraph 0177; 0240; 0241

(2016/07/27)

Asymmetric synthesis of β-fluoroaryl-β-amino acids
The conjugate addition of lithium (R)-N-benzyl-N-(α-methylbenzyl) amide to a range of β-fluoroaryl-α,β-unsaturated esters gave the corresponding β-amino esters with high diastereoselectivity and in good isolated yields. Sequential treatment of the resulta
Davies, Stephen G.,Fletcher, Ai M.,Lv, Linlu,Roberts, Paul M.,Thomson, James E.
p. 910 - 925
(2012/09/22)

Asymmetric synthesis of β-haloaryl β-amino acid derivatives
Lithium N-benzyl-N-α-methyl-4-methoxybenzylamide may be employed as a homochiral ammonia equivalent for the synthesis of homochiral β-haloaryl β-amino acid derivatives via a strategy involving its conjugate addition to α,β-unsaturated β-haloaryl acceptors and subsequent oxidative deprotection with ceric ammonium nitrate.
Bull, Steven D.,Davies, Stephen G.,Delgado-Ballester, Santiago,Kelly, Peter M.,Kotchie, Luke J.,Gianotti, Massimo,Laderas, Mario,Smith, Andrew D.
p. 3112 - 3121
(2007/10/03)

The asymmetric synthesis of β-haloaryl-β-amino acid derivatives
Lithium N-benzyl-N-α-methyl-4-methoxybenzylamide is employed as a homochiral ammonia equivalent for the asymmetric synthesis of β-haloaryl-β-amino acid derivatives using a conjugate addition/oxidative deprotection strategy.
Bull,Davies,Delgado-Ballester,Fenton,Kelly,Smith
p. 1257 - 1260
(2007/10/03)

More Articles about upstream products of 309757-71-9

More Articles about downstream products of 309757-71-9

500789-04-8
(R)-3-(tert-butoxycarbonylamino)-3-(3-fluorophenyl)propanoic acid

Chemical Properties

Boiling Point: 319.2±32.0 °C(Predicted)
Density: 1.102±0.06 g/cm3(Predicted)
PKA: 7.32±0.10(Predicted)
PSA: 52.32000
LogP: 2.73750

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