30994-75-3

Basic information

• Product Name: sapindoside B
• Synonyms: sapindoside B;3β-[[2-O-(3-O-β-D-Xylopyranosyl-α-L-rhamnopyranosyl)-α-L-arabinopyranosyl]oxy]-23-hydroxyolean-12-en-28-oic acid;3β-[[2-O-[6-Deoxy-3-O-(β-D-xylopyranosyl)-α-L-mannopyranosyl]-α-L-arabinopyranosyl]oxy]-23-hydroxy-5α-oleana-12-ene-28-oic acid;3β-[2-O-(3-O-β-D-Xylopyranosyl-α-L-rhamnopyranosyl)-α-L-arabinopyranosyloxy]-23-hydroxyoleana-12-ene-28-oic acid;3β-[2-O-[3-O-(β-D-Xylopyranosyl)-α-L-rhamnopyranosyl]-α-L-arabinopyranosyloxy]-23-hydroxyoleana-12-ene-28-oic acid
• CAS NO: 30994-75-3
• Molecular Formula: C₄₆H₇₄O₁₆
• Molecular Weight: 883.07016
• Mol File: 30994-75-3.mol

Chemical Properties

• Boiling Point: 975.1°Cat760mmHg
• Flash Point: 280.8°C
• Appearance: /
• Density: 1.38g/cm³
• CAS DataBase Reference: sapindoside B(CAS DataBase Reference)
• NIST Chemistry Reference: sapindoside B(30994-75-3)
• EPA Substance Registry System: sapindoside B(30994-75-3)

Safety Data

• Hazardous Substances Data: 30994-75-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Applications:
Sapindoside B is used as a therapeutic agent for its anti-inflammatory, antioxidant, and antifungal properties, offering potential benefits in the treatment of various conditions.
Used in Cancer Treatment:
Sapindoside B is used as a potential cancer treatment agent, with ongoing research exploring its efficacy in targeting and managing cancer cells.
Used in Surfactant and Emulsifier Applications:
Sapindoside B is used as a natural alternative to synthetic surfactants and emulsifiers in various industrial applications, such as cosmetics, detergents, and food processing, due to its foaming and emulsifying properties.
Used in Cosmetics Industry:
Sapindoside B is used as a natural surfactant and emulsifier in the cosmetics industry, providing a safer and eco-friendly alternative to synthetic compounds.
Used in Detergent Industry:
Sapindoside B is used as a natural surfactant in detergent formulations, offering an environmentally friendly option for cleaning products.
Used in Food Processing:
Sapindoside B is used as a natural emulsifier in the food processing industry, improving the stability and texture of various food products.
Further research is necessary to fully understand the potential benefits and risks of sapindoside B for these applications and to optimize its use in various industries.

Upstream product

• 67-56-1 methanol 
• 87733-76-4 mukurozisaponin Y₁ 
• 76729-67-4 hederagenin 3-O-β-D-glucopyranosyl-(1-4)-β-D-glucopyranosyl-(1-4)-β-D-xylopyranosyl-(1-3)-α-L-rhamnopyranosyl-(1-2)-α-L-arabinopyranoside 
• 87733-78-6 hederagenin 3-O-(4-O-acetyl-β-D-xylopyranosyl)-(1->3)-α-L-rhamnopyranosyl-(1->2)-α-L-arabinopyranoside 
• 904684-90-8 hederagenin 3-O-β-D-glucopyranosyl-(1->4)-O-β-D-xylopyranosyl-(1->3)-O-α-L-rhamnopyranosyl-(1->2)-O-α-L-arabinopyranoside 
• 122739-11-1 3-O-β-D-xylopyranosyl-(1->3)-α-L-rhamnopyranosyl-(1->2)-α-L-arabinopyranosyl hederagenin-28-O-β-D-galactopyranosyl-(1->6)-β-D-glucopyranosyl ester 
• 87733-79-7 C₅₀H₇₈O₁₈ 
• 104494-27-1 hishoushi-saponin A 
• 76729-67-4 hederagenin 3-O-β-D-glucopyranosyl-(1->4)-β-D-glucopyranosyl-(1->4)-β-D-ribopyranosyl-(1->3)-α-L-rhamnopyranosyl-(1->2)-α-L-arabinopyranoside 
• 29781-27-9 C₅₂H₈₄O₂₁ 
• 1157918-38-1 hederagenin 3-O-(3,4-di-O-acetyl-α-L-arabinopyranosyl)-(1->3)-α-L-rhamnopyranosyl-(1->2)-4-O-acetyl-α-L-arabinopyranoside 
• 87781-65-5 mukurozi-saponin Y₂ 
• 87733-79-7 hederagenin 3-O-(3,4-O-di-acetyl-α-L-arabinopyranoside)-(1->3)-α-L-rhamnopyranosyl-(1->2)-α-L-arabinopyranoside 
• 119742-55-1 hederagenin-3-O-β-D-xylopyranosyl-(1->3)-O-α-L-rhamnopyranosyl-(1->2)-O-α-L-arabinopyranosyl-28-O-α-L-rhamnopyranosyl-(1->4)-O-β-D-glucopyranosyl-(1->6)-O-β-D-glucopyranosyl ester 

Downstream Products

• 87-72-9 D-Xylose 
• 73-34-7 L-rhamnose 
• 87-72-9 L-(+)-arabinose 
• 465-99-6 hederagenin 
• 27013-91-8 hederagenin 3-O-α-L-rhamnopyranosyl-(1-2)-α-L-arabinopyranoside 
• 17184-21-3 hederogenin 3-O-α-L-arabinopyranoside 
• 27013-91-8 alpha-Hederin 

Relevant articles and documents

Antimicrobially active hederagenin glycosides from Cephalaria elmaliensis

A phytochemical investigation of the aerial parts of Cephalaria elmaliensis resulted in the isolation of ten hederagenin-type triterpene saponins (1-10) including three new ones, elmalienoside A (1), elmalienoside B (2), elmalienoside C (3), and two known flavonoid glycosides (11-12). Their structures were identified by extensive spectroscopic techniques (1D and 2D NMR, HR ESIMS) and chemical evidence. The antimicrobial activity of the extracts and the pure compounds was evaluated by the MIC method. According to the results, all pure compounds including the new ones were found to be very active against both gram-positive and gram-negative bacteria. Georg Thieme Verlag KG Stuttgart · New York.

Structures of acetylated oleanane-type triterpene saponins, rarasaponins IV, V, and VI, and anti-Hyperlipidemic constituents from the pericarps of sapindus rarak

The methanolic extract and its saponin fraction (methanol-eluted fraction) of the pericarps of Sapindus rarak DC. were found to suppress plasma triglyceride elevation in olive oil-treated mice. From the active fraction, three new acylated oleanane-type tr

Triterpene glycosides from Kalopanax septemlobum. II. Glycosides E, K, and L from leaves of Kalopanax septemlobum var. maximowiczii introduced to Crimea

The known hederagenin 3-O-β-D-glucopyranosyl-(1→4)-O-β-D- xylopyranosyl-(1→3)-O-α-L-rhamnopyranosyl-(1→2) -O-α-L-arabinopyranoside (sapindoside C) and its 28-O-α-L- rhamnopyranosyl-(1→4)-β-D-glucopyranosyl-(1→6) -O-β-D-glucopyranosyl and 28-O-α-L-rhamnopyranosyl-(1→4)-O-6-O- acetyl-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl esters, new triterpene glycosides, were isolated from leaves of Kalopanax septemlobum var. maximowiczii introduced to Crimea. The structures of these compounds were established using chemical methods and two-dimensional NMR spectroscopy. 2005 Springer Science+Business Media, Inc.

Triterpene glycosides from Kalopanax septemlobum. 1. Glycosides A, B, C, F, G1, G2, I2, H, and J from leaves of Kalopanax septemlobum var. maximowichii introduced to Crimea

Eight known glycosides of hederagenin and the new triterpene glycoside 3-O-β-D-xylopyranosyl-(1→3)-O-α-L-rhamnopyranosyl-(1→2) -O-α-L-arabinopyranosyl-28-O-α-L-rhamnopyranosyl-(1→4) -O-6-O-acetyl-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl ester of hederagenin were isolated by chromatographic methods from leaves of Kalopanax septemlobum var. maximowichii introduced to Crimea. The known 3-O-α-L-arabinopyranosyl-28-O-α-L-rhamnopyranosyl-(1→4) -O-6-O-acetyl-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl ester of hederagenin was observed for the first time in Kalopanax septemlobum. 2005 Springer Science + Business Media, Inc.

Metabolism of kalopanaxsaponin K by human intestinal bacteria and antirheumatoid arthritis activity of their metabolites.

When kalopanaxsaponin K (KPK) from Kalopanax pictus was incubated for 24 h at 37 degrees C with human intestinal microflora, KPK was mainly metabolized to kalopanaxsaponin I (KPI) via kalopanaxsaponin H (KPH) rather than via kalopanaxsaponin J (KPJ), and then transformed to kalopanaxsaponin A (KPA) and hederagenin. Bacteroides sp., and Bifidobacterium sp. and Fusobacterium sp. transformed KPK to KPI and KPA and hederagenin via KPH or KPJ. However, Lactobacillus sp. and Streptococcus sp. transformed KPK to KPI, KPA, and hederagenin only via KPJ. The metabolite KPA of KPK showed potent antirheumatoid arthritis activity.

Antifungal activity of modified hederagenin glycosides from the leaves of Kalopanax pictum var. chinense

Monodesmosides which were obtained from the partial degradation of hederagenin bisdesmosides exhibited significant antifungal effect against Microsporum canis, Coccidioides immitis, Trichophyton mentagrophytes, Cryptococcus neoformans, and Candida albican

Acetylated triterpene saponins from the Thai medicinal plant, Sapindus emarginatus

From the pericarps of Sapindus emarginatus (Sapindaceae), three new acetylated triterpene saponins were isolated together with hederagenin and five known triterpene saponins, as well as one known sweet acyclic sesquiterpene glycoside, mukurozioside IIb. T

Triterpenoid glycosides from Decaisnea fargesii Franch

A new triterpenoid glycoside, 3-O-β-D-xylopyranosyl (1 → 3)-α-L- rhamnopyranosyl (1 → 2)-α-L-arabinopyranosyl hederagenin 28-O-β-D- xylopyranosyl (1 → 4)-β-D-glucopyranosyl (1 → 6)-β-D-glucopyranoside 1, named decaisoside F, has been isolated from the seeds of Decaisnea fargesii along with two known compounds, decaisoside D 2 and decaisoside E 3. Their structures have been elucidated on basis of chemical methods and spectral data (FABMS, 1H NMR, 13C NMR. DEPT and COSY).

Metabolism of kalopanaxsaponin B and H by human intestinal bacteria and antidiabetic activity of their metabolites

To investigate the relationship between the intestinal bacterial metabolism of kalopanaxsaponin B and H from Kalopanax pictus (Araliaceae), and their antidiabetic effect, kalopanaxsaponin B and H were metabolized by human intestinal microflora and the antidiabetic activity of their metabolites was measured. Human intestinal microflora metabolized kalopanaxsaponin B to kalopanaxsaponin A, hederagenin 3-O-α-L- arabinopyranoside and hederagenin. The main metabolites of kalopanaxsaponin B were kalopanaxsaponin A and hederagenin. Kalopanaxsaponin H was metabolized to kalopanaxsaponin A and I, hederagenin 3-O-α-L-arabinopyranoside and hederagenin. The main metabolites of kalopanaxsaponin H were kalopanaxsaponin I and hederagenin. Among kalopanaxsaponin B, H and their metabolites, kalopanaxsaponin A showed the most potent antidiabetic activity, followed by hederagenin. However, the main components, kalopanaxsaponin B and H, in K. pictus were inactive.