314283-98-2

Basic information

• Product Name: N-benzylidene-2-methyl-3-nitroaniline
• Synonyms: N-benzylidene-2-methyl-3-nitroaniline
• CAS NO: 314283-98-2
• Molecular Formula: C₁₄H₁₂N₂O₂
• Molecular Weight: 240.25728
• Mol File: 314283-98-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-benzylidene-2-methyl-3-nitroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzylidene-2-methyl-3-nitroaniline(314283-98-2)
• EPA Substance Registry System: N-benzylidene-2-methyl-3-nitroaniline(314283-98-2)

Safety Data

• Hazardous Substances Data: 314283-98-2(Hazardous Substances Data)

Upstream product

• 603-83-8 3-nitro-o-tolylamine 
• 100-51-6 benzyl alcohol 
• 100-52-7 benzaldehyde 

Downstream Products

• 375856-45-4 N-benzyl-2-methyl-3-nitroaniline 

Relevant articles and documents

Bi-functional catalyst of porous N-doped carbon with bimetallic FeCu for solvent-free resultant imines and hydrogenation of nitroarenes

The efficient and stable catalyst applied to the transformation of amines into the corresponding imines and hydrogenation of nitroarenes under mild reaction conditions is reported. The catalytic performance of porous N-doped carbon with FeCu (FeCu@NPC) catalyst are tested by aromatic alcohol-based N-alkylated of amines with solvent-free and hydrogenation of nitroarenes via N2H4·H2O. The results proved that the yield of these two reactions are all over 99.9% under optimum condition. Moreover, the synergistic effect of the catalyst for N-alkylated reaction was investigated through the kinetic study. The catalyst can be easily separated from reaction system by an external magnetism, and can be recycled and reutilized for at least 4 runs with conversions are all over 75%. The study of the catalyst indicated that it was suitable for the reactions in industry. Hence, the catalysis process by the inexpensive metals-based catalyst is green and sustainable.

Discovery of novel nonsteroidal glucocorticoid receptor modulators

A new class of selective nonsteroidal glucocorticoid receptor modulators typified by N-{3-[benzyl-(4-chloro-2-fluoro-benzyl)-amino]-2-methyl-phenyl}- methanesulfonamide 19 has been discovered.

Bile acid conjugates of a nonsteroidal glucocorticoid receptor modulator

Bile acid conjugates of a selective nonsteroidal glucocorticoid receptor modulator were prepared and evaluated. Potent GR binding conjugates that showed improved metabolic stability were discovered. However, cellular potency and pharmacokinetics were not substantially improved.