- Efficient one-step synthesis of benzazoles in aqueous media
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Benzazoles (benzoxazoles, benzothiazoles, and benzimidazoles) were efficiently prepared by the aquatic reaction of the corresponding thioamidinium salts and 2-aminophenol, 2-aminothiophenol, and 1,2-diaminobenzene, respectively. The thioamidinium salt was successfully applied as an alternative to a carboxylic acid derivative to react smoothly with an amino precursor and in the presence of catalytic amounts of hexadecyltrimethylammonium bromide salt to produce benzazoles in good to excellent yields. Wiley-VCH Verlag GmbH & Co. KGaA 2009.
- Boeini, Hassan Zali,Najafabadi, Khadijeh Hajibabaei
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supporting information; experimental part
p. 4926 - 4929
(2010/01/18)
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- Polarized Ethylenes. IV. Synthesis of Polarized Ethylenes Using Thioamides and Methyl Dithiocarboxylates and their Application to Syntheses of Pyrazoles, Pyrimidines, Pyrazolopyrimidines, and 5-Azacyclazines
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Polarized ethylenes having both electron-donating (an amino or a methylthio group) and electron-accepting (cyano, carbamoyl, methyl ester) groups on the adjacent two olefinic carbon atoms were prepared by the condensation of S-alkylthioamidinium salts or
- Tominaga, Yoshinori,Matsuoka, Yoshiki,Oniyama, Yukio,Uchimura, Yoshimitsu,Komiya, Hirofumi,et al.
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p. 647 - 660
(2007/10/02)
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- HIGHLY COORDINATE ORGANOSILICON COMPOUNDS IN SYNTHESIS: NEW ENTRY TO S,N-ACETALS BY SELECTIVE REDUCTION OF ALKYLTHIOMETHYLENIMINIUM SALTS BY USE OF TRIMETHOXYSILANE AND DILITHIUM 2,3-BUTANDIOLATE
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Reduction of alkylthiomethyleniminium iodides proceeds smoothly by use of trimethoxysilane and dilithium 2,3-butandiolate in tetrahydrofuran at 0 deg C to give the corresponding S,N-acetals selectively in high yield.
- Tominaga, Yoshinori,Matsuoka, Yoshiki,Hayashida, Hisashi,Kohra, Shinya,Hosomi, Akira
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p. 5771 - 5774
(2007/10/02)
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- Studies on Thioamides and Their Derivatives,VI. New Synthesis of 5-Membered Heterocyclic Compounds
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Simple N-monosubstituted thioamides react with acid hydrazides to form 1,2,4-triazole derivatives.N,N-Disubstituted thioamides alkylated with methyl iodide readily yield with acid hydrazides 1,3,4-oxadiazoles.
- Santus, Maria
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p. 179 - 182
(2007/10/02)
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- Reactions of S-Alkyl-N,N-disubstituted Thioamide Salts. Part 4. Sulphenamidine Derivatives
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Readily available 3-(α-dialkylaminoalkylidene)-1-alkylthiotriazenes (1) with C-aryl, benzyl, or isopropyl substituents, on being stirred with copper(I) cyanide or copper powder in dichloromethane or toluene solution at room temperature or below, give sulp
- Stansfield, Frank
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p. 2933 - 2935
(2007/10/02)
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