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Monosodium glutamate (MSG) is the sodium salt of the amino acid glutamic acid, a white crystalline solid compound made from soya-bean protein. It is used as a flavor enhancer, particularly in Chinese cuisine, and is known for its ability to intensify and enhance the flavor of foods without contributing a distinct flavor of its own. MSG is odorless and works synergistically with other substances found in food proteins, such as the nucleotides disodium 5'-inosine monophosphate (IMP) and disodium 5'-guanosine monophosphate (GMP), to produce a pleasing savory taste.

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  • 32221-81-1 Structure
  • Basic information

    1. Product Name: Monosodium glutamate
    2. Synonyms: DL-monosodium glutamate;sodium glutamate(1-);sodium acid l-glutamate;Monosodium glutamate;Sodium 5-oxido-5-oxonorvaline;Monosodium glutamate with other flavour-enhancers;α-Amiopetandioic acid monosodium salt;Glutamic acid, monosodium salt, DL-
    3. CAS NO:32221-81-1
    4. Molecular Formula: C5H7NO4*2Na
    5. Molecular Weight: 169.11109
    6. EINECS: 200-533-0
    7. Product Categories: N/A
    8. Mol File: 32221-81-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 333.8 °C at 760 mmHg
    3. Flash Point: 155.7 °C
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. Stability: Stable. Incompatible with strong oxidizing agents
    10. CAS DataBase Reference: Monosodium glutamate(CAS DataBase Reference)
    11. NIST Chemistry Reference: Monosodium glutamate(32221-81-1)
    12. EPA Substance Registry System: Monosodium glutamate(32221-81-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 32221-81-1(Hazardous Substances Data)

32221-81-1 Usage

Uses

Used in Food Industry:
Monosodium glutamate is used as a flavor enhancer for its ability to intensify and enhance the flavor of foods. It is used at 0.1–1.0% in meats, soups, and sauces, and is particularly popular in Chinese cuisine.
Used in Agricultural Feed Supplements:
A small portion of MSG is used as an agricultural feed supplement, specifically for swine, to improve the taste and nutritional value of their feed.
Used in Pesticides and Pharmaceuticals:
Although a minor application, MSG is also used in the production of pesticides and pharmaceuticals due to its unique properties.

History

The use of Monosodium glutamate(MSG) as a flavor enhancer is attributed to Kikunae Ikeda (1864 1936), a chemistry professor from Tokyo Imperial University. Ikeda patented Monosodium glutamate(MSG) as a flavor enhancer along with processes used to produce it. The isolated glutamic acid was then purified and converted to MSG. The use of Monosodium glutamate(MSG) as a flavor enhancer began in Japan and Asia, but widespread use of the compound in the United States did not occur until after World War II. Ajinomoto started manufacturing Monosodium glutamate(MSG) in the United States in 1956 (Ajinomoto became affiliated with Kraft General Foods in 1973).

Check Digit Verification of cas no

The CAS Registry Mumber 32221-81-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,2,2 and 1 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 32221-81:
(7*3)+(6*2)+(5*2)+(4*2)+(3*1)+(2*8)+(1*1)=71
71 % 10 = 1
So 32221-81-1 is a valid CAS Registry Number.
InChI:InChI=1/C5H9NO4.Na/c6-3(5(9)10)1-2-4(7)8;/h3H,1-2,6H2,(H,7,8)(H,9,10);/q;+1/p-1

32221-81-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name Monosodium glutamate

1.2 Other means of identification

Product number -
Other names Sodium 5-oxido-5-oxonorvaline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:32221-81-1 SDS

32221-81-1Relevant articles and documents

CATALYTIC POTENCY OF FUNCTIONALIZED (2,5)PYRIDINOPHANES AS NEW PYRIDOXAL MODEL COMPOUNDS

Iwata, Masaaki,Kuzuhara, Hiroyoshi

, p. 5 - 6 (1981)

Catalytic activities of new model compounds, 1a-c, 2, and 3, for the racemization of monosodium L-glutamate were shown to be more potent, ca. 1.5 fold, than that of pyridoxal, and catalyst, 1a, was stable enough to show no decomposition throughout the reaction.

CAGED COMPOUND, AND MANUFACTURING METHOD AND EXPRESSION METHOD OF CAGED COMPOUND

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Paragraph 0166; 0167, (2019/03/01)

PROBLEM TO BE SOLVED: To provide a caged compound excellent in light reactivity and dark place stability, and capable of deprotection by a visible light. SOLUTION: A caged compound is represented by the following general formula (1). In the general formula (1), R1 represents a hydrogen atom, a halogen atom, an alkyl group, an aryl group, a cyano group, an alkoxy group, a hydroxy group, or an alkylamino group, R2 represents an alkyl group or a hetero atom other than a nitrogen atom, R3 represents a hydrogen atom, a halogen atom or an alkyl group, X represents a monovalent anion, Y represents a monovalent organic group, Z represents a hydrogen atom or a monovalent organic group, and a represents 0 or 1, however a represents 0 when R2 represents the hetero atom other than the nitrogen atom. SELECTED DRAWING: None COPYRIGHT: (C)2019,JPOandINPIT

Silicon nanowire photocathodes for light-driven electroenzymatic synthesis

Lee, Sahng Ha,Ryu, Gyeong Min,Nam, Dong Heon,Kim, Jae Hong,Park, Chan Beum

, p. 3007 - 3011 (2015/09/28)

The photoelectroenzymatic synthesis of chemical compounds employing platinum nanoparticle-decorated silicon nanowires (Pt-SiNWs) is presented. The Pt-SiNWs proved to be an efficient material for photoelectrochemical cofactor regeneration because the silicon nanowires absorbs a wide range of the solar spectrum while the platinum nanoparticle serve as an excellent catalyst for electron and proton transfer. By integrating the platform with redox enzymatic reaction, visible-light-driven electroenzymatic synthesis of L-glutamate was achieved. Compared to electrochemical and photochemical methods, this approach is free from side reactions caused by sacrificial electron donors and has the advantage of applying low potential to realize energy-efficient and sustainable synthesis of chemicals by a photoelectroenzymatic system.

Process for chemical reaction of amino acids and amides yielding selective conversion products

-

Page 7-8, (2008/06/13)

The invention relates to processes for converting amino acids and amides to desirable conversion products including pyrrolidines, pyrrolidinones, and other N-substituted products. L-glutamic acid and L-pyroglutamic acid provide general reaction pathways to numerous and valuable selective conversion products with varied potential industrial uses.

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