330796-32-2Relevant articles and documents
Mediators of hedgehog signaling pathways, compositions and uses related thereto
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Page/Page column 75; 76, (2015/11/27)
The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function by contacting the cell with a hedgehog antagonist, such as a small molecule, in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize hedgehog activity.
Quinazolinone fungal efflux pump inhibitors. Part 2: In vitro structure-activity relationships of (N-methyl-piperazinyl)-containing derivatives
Watkins, William J.,Lemoine, Rémy C.,Chong, Lee,Cho, Aesop,Renau, Thomas E.,Kuo, Bonnie,Wong, Vickie,Ludwikow, Maria,Garizi, Negar,Iqbal, Nadeem,Barnard, John,Jankowska, Renata,Singh, Rajeshwar,Madsen, Deidre,Lolans, Karen,Lomovskaya, Olga,Oza, Uma,Dudley, Michael N.
, p. 5133 - 5137 (2007/10/03)
Structure-activity relationships of a novel series of fungal efflux pump inhibitors with respect to potentiation of the activity of fluconazole against strains of Candida albicans and Candida glabrata over-expressing ABC-type efflux pumps are systematical
Mediators of hedgehog signaling pathways, compositions and uses related thereto
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, (2008/06/13)
The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function by contacting the cell with a hedgehog antagonist, such as a small molecule, in a sufficient amount to aberrant growt