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3-AMINO-4-DIMETHYLAMINO-THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 3-AMINO-4-DIMETHYLAMINO-THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER

    Cas No: 331857-03-5

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  • 331857-03-5 Structure
  • Basic information

    1. Product Name: 3-AMINO-4-DIMETHYLAMINO-THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
    2. Synonyms: 3-AMINO-4-DIMETHYLAMINO-THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER;Methyl 3-amino-4-dimethylamino-thieno[2,3-b]pyridine-2-carboxylate
    3. CAS NO:331857-03-5
    4. Molecular Formula: C11H13N3O2S
    5. Molecular Weight: 0
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 331857-03-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 3-AMINO-4-DIMETHYLAMINO-THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3-AMINO-4-DIMETHYLAMINO-THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER(331857-03-5)
    11. EPA Substance Registry System: 3-AMINO-4-DIMETHYLAMINO-THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER(331857-03-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 331857-03-5(Hazardous Substances Data)

331857-03-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 331857-03-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,1,8,5 and 7 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 331857-03:
(8*3)+(7*3)+(6*1)+(5*8)+(4*5)+(3*7)+(2*0)+(1*3)=135
135 % 10 = 5
So 331857-03-5 is a valid CAS Registry Number.

331857-03-5Relevant articles and documents

FUSED TRICYCLIC MGLUR1 ANTAGONISTS AS THERAPEUTIC AGENTS

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Page/Page column 45; 49, (2010/11/26)

In its many embodiments, the present invention provides tricyclic compounds of formula I (wherein J1-J3, X, Z, and R1-R4 are as defined herein) useful as metabotropic glutamate receptor (mGluR) antagonists, part

Fused tricyclic mGIuR1 antagonists as therapeutic agents

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Page/Page column 23; 20, (2010/11/26)

In its many embodiments, the present invention provides tricyclic compounds of formula I (wherein J1-J3, X, Z, and R1, R3, and R4 are as defined herein) useful as metabotropic glutamate receptor (mGlu

ANTAGONISTS OF THE MGLU RECEPTOR AND USES THEREOF

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Page/Page column 31, (2008/06/13)

The present invention discloses compounds of general formula (I) wherein X1-X4 and R1-R3 are as defined in the description. The present invention also discloses methods of treatment for pain, neurodegeneration and convulsive states in a host mammal in need thereof, and pharmaceutical compositions including those compounds.

mGluR1 antagonists as therapeutic agents

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Page/Page column 66; 82, (2008/06/13)

In its many embodiments, the present invention provides tricyclic compounds of formula I (wherein J1-J4, X, and R1—R5 are as defined herein) useful as metabotropic glutamate receptor (mGluR) antagonists, particularly as selective metabotropic glutamate receptor 1 antagonists, pharmaceutical compositions containing the compounds, and methods of treatment using the compounds and compositions to treat diseases associated with metabotropic glutamate receptor (e.g., mGluR1) such as, for example, pain, migraine, anxiety, urinary incontinence and neurodegenerative diseases such Alzheimer's disease.

Structure-activity relationship of triazafluorenone derivatives as potent and selective mGluR1 antagonists

Zheng, Guo Zhu,Bhatia, Pramila,Daanen, Jerome,Kolasa, Teodozyj,Patel, Meena,Latshaw, Steven,El Kouhen, Odile F.,Chang, Renjie,Uchic, Marie E.,Miller, Loan,Nakane, Masaki,Lehto, Sonya G.,Honore, Marie P.,Moreland, Robert B.,Brioni, Jorge D.,Stewart, Andrew O.

, p. 7374 - 7388 (2007/10/03)

SAR (structure-activity relationship) studies of triazafluorenone derivatives as potent mGluR1 antagonists are described. The triazafluorenone derivatives are non-amino acid derivatives and noncompetitive mGluR1 antagonists that bind at a putative alloste

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