33630-25-0

Basic information

• Product Name: 2-Phenyl-4-aminopyrimidine
• Synonyms: 2-Phenyl-4-aminopyrimidine;4-Amino-2-Phenylpyrimidine;2-Phenylpyrimidin-4-amine
• CAS NO: 33630-25-0
• Molecular Formula: C₁₀H₉N₃
• Molecular Weight: 171.19856
• Mol File: 33630-25-0.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 2-Phenyl-4-aminopyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Phenyl-4-aminopyrimidine(33630-25-0)
• EPA Substance Registry System: 2-Phenyl-4-aminopyrimidine(33630-25-0)

Safety Data

• Hazardous Substances Data: 33630-25-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical and Agrochemical Synthesis:
2-Phenyl-4-aminopyrimidine is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals for its ability to form the basis of various substances with potential therapeutic and agricultural applications.
Used in Organic Chemistry Research:
PAP is used as a building block in organic chemistry research to explore its reactivity and potential to form new compounds with unique properties.
Used in Medicine and Related Fields:
2-Phenyl-4-aminopyrimidine is used as a potential candidate for applications in medicine and related fields due to its demonstrated bioactivity and potential for further development in therapeutic areas.

Upstream product

• 14790-42-2 4-chloro-2-phenylpyrimidine 
• 7664-41-7 ammonia 
• 140367-35-7 (E)-[1-cyano-2-(methylsulfanyl)vinyl]triphenylphosphonium iodide 
• 618-39-3 benzamidin 
• 7461-50-9 2-chloropyrimidin-4-amine 
• 98-80-6 phenylboronic acid 
• 61310-53-0 3-ethoxyacrylonitrile 

Downstream Products

• 1246562-29-7 2-(4-acetamidopyrimidin-2-yl)phenyl acetate 
• 33630-29-4 N-(2-phenylpyrimidin-4-yl)acetamide 
• 1300056-91-0 1-[1-(3-diethylaminopropyl)-1H-indol-3-yl]-3-(2-phenylpyrimidin-4-yl)urea 
• 14790-42-2 4-chloro-2-phenylpyrimidine 

Relevant articles and documents

HETEROARYLS AND USES THEREOF

The present invention provides a compound of formula I: and pharmaceutically acceptable salts thereof, wherein X, R1, R2, R3, R4, R5, L1, L2, m, and n, are as described in the specification. Such compounds are inhibitors of VPS34 and thus useful for treating proliferative, inflammatory, or cardiovascular disorders.

HETEROARYLS AND USES THEREOF

The present invention provides a compound of formula I: and pharmaceutically acceptable salts thereof, wherein X, R1, R2, R3, R4, R5, L1, L2, m, and n, are as described in the specification. Such compounds are inhibitors of VPS34 and thus useful for treating proliferative, inflammatory, or cardiovascular disorders.

The synthesis and evaluation of indolylureas as PKCα inhibitors

PKCα and PKA have crucial but opposing roles in the regulation of calcium handling within myocytes. Identification of compounds that inhibit PKCα, but not PKA, are potential therapeutic targets for the treatment of heart disease. The synthesis of indolylureas are described, and a compound displaying nanomolar inhibition towards PKCα with significant selectivity over PKA has been identified.

Palladium-Catalyzed Regioselective C-H Bond ortho-Acetoxylation of Arylpyrimidines

An efficient and regioselective palladium-catalyzed ortho C-H acetoxylation reaction was developed to afford, ortho monoacetoxylated arylpyrimidmes in good to excellent yields by using cupric trifluoroacetate as a cocatalyst. A wide variety of oxygenated

Cyclocondensation of [1-cyano-2-(methylsulfanyl)vinyl]triphenylphosphonium iodide with amidine nucleophiles

The substituted vinylphosphonium salt (E)-MeSCH=C(CN)P+Ph 3I- readily cyclizes under the action of benzamidine and 3-amino-s-triazole, but it does not enter cyclocondensation with 2-aminopyridine. The structure of the cycl

11B-HSD1 inhibitors for the treatment of diabetes

Compounds of the formula (I): as well as pharmaceutically acceptable salts and esters thereof, wherein R1 to R5 have the significance given in claim 1 can be used in the form of pharmaceutical compositions.