34466-20-1

Basic information

• Product Name: Ribose (9CI)
• Synonyms: Ribose (9CI)
• CAS NO: 34466-20-1
• Molecular Formula: C₅H₁₀O₅
• Molecular Weight: 150.1299
• Product Categories: CARBOHYDRATE
• Mol File: 34466-20-1.mol

Chemical Properties

• Boiling Point: 375.4°Cat760mmHg
• Flash Point: 180.8°C
• Appearance: /
• Density: 1.681g/cm³
• CAS DataBase Reference: Ribose (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ribose (9CI)(34466-20-1)
• EPA Substance Registry System: Ribose (9CI)(34466-20-1)

Safety Data

• Hazardous Substances Data: 34466-20-1(Hazardous Substances Data)

Upstream product

• 50-69-1 D-ribose 
• 24259-59-4 L-ribose 
• 453-17-8 D-Glyceraldehyde 
• 141-46-8 Glycolaldehyde 
• 56-82-6 Glyceraldehyde 
• 96-26-4 dihydroxyacetone 
• 19192-62-2 Ribo-pentodialdose 
• 7732-18-5 water 
• 4495-04-9 1,2-O-isopropylidene-α-D-allofuranose 
• 1949-78-6 L-lyxose 
• 1114-34-7 D-lyxose 
• 608-66-2 D-galactitol 
• 50-00-0 formaldehyd 
• 2595-05-3 Diacetone D-glucose 

Downstream Products

• 528869-25-2 (3S,4R,5R)-2-Bromo-tetrahydro-pyran-3,4,5-triol 
• 87614-58-2 (3S,4S)-3-(2-Hydroxy-ethyl)-3,4-dihydro-2H-pyran-4-ol 
• 87614-59-3 (3S,4S)-3-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-3,4-dihydro-2H-pyran-4-ol 
• 75452-45-8 C₂₅H₄₀O₆ 
• 87614-60-6 2-{(2S,5R)-5-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-5,6-dihydro-2H-pyran-2-yl}-N,N-dimethyl-acetamide 
• 87641-25-6 C₃₆H₅₀O₆Si 
• 87614-61-7 C₄₀H₄₄O₇Si 
• 85620-84-4 1,5-anhydro-2,3-dideoxy-D-glycero-pent-2-enitol 
• 87614-56-0 5S-iodo-1S,6S-3,7-dioxabicyclo<4,3,0>nonan-8-one 
• 85620-85-5 3R-3,6-dihydro-2H-pyranyl-N,N-dimethylacetamide 
• 87678-98-6 1-{(2S,5R)-5-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-5,6-dihydro-2H-pyran-2-yl}-propan-2-one 
• 87678-99-7 1-{(2S,3R,4R,5S)-5-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-3,4-dihydroxy-tetrahydro-pyran-2-yl}-propan-2-one 
• 71980-98-8 pseudomonic acid C 
• 12650-69-0 mupirocin 

Relevant articles and documents

Synthesis of racemic ribose from D-glucose

Racemic ribose is a valuable starting material for investigations of the origins of biomolecular homochirality. It can be synthesized in seven steps starting from D-glucose.

Kinetics, Catalysis, and Mechanism of the Secondary Reaction in the Final Phase of the Formose Reaction

In the final phase of the formose reaction sugars are formed by the reaction of glycolaldehyde, glyceraldehyde and dihydroxyacetone.The application of high-pressure liquid chromatography allows for the first time to investigate intermediate and final products quantitatively.The results of kinetical investigations allow to suggest a reaction mechanism for the secondary reaction in the final phase of the formose reaction.This mechanism is compared with that of the starting phase and other known mechanisms.From the results metal ion-catalyzed aldol reactions have to be assumed.

THE FORMOIN REACTION

The formoin reaction, i.e., the autocondensation of formaldehyde in an aprotic solvent catalysed by the conjugate base of a thiazolium ion, has been studied in detail.Glucose, galactose, dihyroxyacetone dimer, xylose, and arabinose have been identified as products.The influence of catalysts, temperature, basicity, and reaction time is documented.N,N-Dimethylformamide is a more convenient solvent than ether, benzene, or diglyme.Ethyldi-isopropylamine affords better yields of carbohydrate material than triethylamine.At =60 deg, aldol condensations are reduced to a minimum.After 1-2 h of reaction (depending on the conditions), the yields begin to decrease and become zero after ca. 24 h.