348640-19-7 Usage
Uses
Used in Pharmaceutical Industry:
3-Borono-5-methoxy-1H-indole-1-carboxylic acid 1-(1,1-dimethylethyl) ester is used as a key intermediate in the synthesis of new pharmaceutical compounds for the treatment of cancer. Its boron atom's ability to interact with biological targets makes it a promising candidate for the development of targeted therapies that can selectively affect cancer cells.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 3-Borono-5-methoxy-1H-indole-1-carboxylic acid 1-(1,1-dimethylethyl) ester serves as a valuable compound for studying the structure-activity relationships of potential drug molecules. Its unique chemical properties allow researchers to explore its interactions with various biological targets, aiding in the design of more effective and selective drugs.
Used in Organic Synthesis:
3-Borono-5-methoxy-1H-indole-1-carboxylic acid 1-(1,1-dimethylethyl) ester is utilized as a versatile building block in organic synthesis, enabling the creation of a wide range of chemical entities. Its reactivity and functional groups make it suitable for various synthetic transformations, broadening its applicability in the synthesis of complex organic molecules and potential drug candidates.
Used in the Development of Anti-Inflammatory Agents:
Given its potential role in modulating biological processes, 3-Borono-5-methoxy-1H-indole-1-carboxylic acid 1-(1,1-dimethylethyl) ester is also considered for use in the development of anti-inflammatory agents. Its ability to interact with specific biological targets may offer a new approach to treating inflammatory diseases by modulating the underlying inflammatory pathways.
Check Digit Verification of cas no
The CAS Registry Mumber 348640-19-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,8,6,4 and 0 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 348640-19:
(8*3)+(7*4)+(6*8)+(5*6)+(4*4)+(3*0)+(2*1)+(1*9)=157
157 % 10 = 7
So 348640-19-7 is a valid CAS Registry Number.
348640-19-7Relevant articles and documents
Design of potent IGF1-R inhibitors related to bis-azaindoles
Nemecek, Conception,Metz, William A.,Wentzler, Sylvie,Ding, Fa-Xiang,Venot, Corinne,Souaille, Catherine,Dagallier, Anne,Maignan, Sebastien,Guilloteau, Jean-Pierre,Bernard, Francois,Henry, Alain,Grapinet, Sandrine,Lesuisse, Dominique
scheme or table, p. 100 - 106 (2011/03/19)
From an azaindole lead, identified in high throughput screen, a series of potent bis-azaindole inhibitors of IGF1-R have been synthesized using rational drug design and SAR based on a in silico binding mode hypothesis. Although the resulting compounds produced the expected improved potency, the model was not validated by the co-crystallization experiments with IGF1-R.
