35237-63-9

Basic information

• Product Name: TRANS-10-DODECENOL
• Synonyms: TRANS-10-DODECENOL;(E)-10-Dodecen-1-ol;trans-10-dodecanol;dodec-10-(E)-en-1-ol
• CAS NO: 35237-63-9
• Molecular Formula: C₁₂H₂₄O
• Molecular Weight: 184.31836
• Mol File: 35237-63-9.mol

Chemical Properties

• Boiling Point: 248.6°C at 760 mmHg
• Flash Point: 105.4°C
• Appearance: /
• Density: 0.846g/cm³
• Vapor Pressure: 0.00387mmHg at 25°C
• Refractive Index: 1.456
• Storage Temp.: 2-8°C
• PKA: 15.20±0.10(Predicted)
• CAS DataBase Reference: TRANS-10-DODECENOL(CAS DataBase Reference)
• NIST Chemistry Reference: TRANS-10-DODECENOL(35237-63-9)
• EPA Substance Registry System: TRANS-10-DODECENOL(35237-63-9)

Safety Data

• Hazardous Substances Data: 35237-63-9(Hazardous Substances Data)

Usage

Uses

Used in Biological Studies:
TRANS-10-DODECENOL is used as a compound in the biological study of inhibition of Chlorella growth. It is involved in the degradation process of linoleic and linolenic acids, which are essential polyunsaturated fatty acids (PUFAs) found in phytoplankton. The study aims to understand the significance of these PUFAs in phytoplankton ecology and their potential impact on the growth and development of these microscopic organisms.

InChI:InChI=1/C12H24O/c1-2-3-4-5-6-7-8-9-10-11-12-13/h2-3,13H,4-12H2,1H3/b3-2+

Upstream product

• 69221-99-4 dodec-10-yn-1-ol 
• 112-47-0 1,10-Decanediol 
• 175914-87-1 10-(methoxymethoxy)decan-1-ol 
• 2774-84-7 undec-10-yn-1-ol 
• 2777-65-3 undec-10-ynoic acid 
• 112-38-9 10-undecenoic acid 
• 51953-88-9 1-[(tetrahydropyran-2-yl)oxy]undec-10-yne 
• 86252-56-4 1-(tetrahydropyran-2'-yloxy)-dodec-10-yne 
• 736177-58-5 ethyl (E)-12-methoxymethoxydodec-2-enoate 
• 736177-60-9 (E)-12-methoxymethoxydodec-2-en-1-ol 
• 736177-62-1 (E)-12-methoxymethoxydodec-2-ene 

Downstream Products

• 35153-09-4 (E)-10-dodecenyl acetate 
• 148751-11-5 trans-10-dodecenoic acid 

Relevant articles and documents

Using stereoretention for the synthesis of e -macrocycles with ruthenium-based olefin metathesis catalysts

The synthesis of E-macrocycles is achieved using stereoretentive, Ru-based olefin metathesis catalysts supported by dithiolate ligands. Kinetic studies elucidate marked differences in activity among the catalysts tested, with catalyst 4 providing meaningful yields of products in much shorter reaction times than stereoretentive catalysts 2 and 3. Macrocycles were generated with excellent selectivity (>99% E) and in moderate to high yields (47-80% yield) from diene starting materials bearing two E-configured olefins. A variety of rings were constructed, ranging from 12- to 18-membered macrocycles, including the antibiotic recifeiolide.

Enzyme-substrate complementarity governs access to a cationic reaction manifold in the P450BM3-catalysed oxidation of cyclopropyl fatty acids

The products of cytochrome P450BM3-catalysed oxidation of cyclopropyl-containing dodecanoic acids are consistent with the presence of a cationic reaction intermediate, which results in efficient dehydrogenation of the rearranged probes by the enzyme. These results highlight the importance of enzyme-substrate complementarity, with a cationic intermediate occurring only when the probes used begin to diverge from ideal substrates for this enzyme. This also aids in reconciling literature reports supporting the presence of cationic intermediates with certain cytochrome P450 enzyme/substrate pairs.

Structural requirements of dictyopyrones isolated from Dictyostelium spp. in the regulation of Dictyostelium development and in anti-leukemic activity

Cellular slime molds are fascinating to the field of developmental biology, and have long been used as excellent model organisms for the study of various aspects of multicellular development. We have recently isolated α-pyronoids, named dictyopyrones A-D (1-4), from various species of Dictyostelium cellular slime molds, and it was shown that compound 3 may regulate Dictyostelium development. In this study, we synthesized dictyopyrones A-D (1-4) and their analogues, investigated the physiological role of the molecules in cell growth and morphogenesis in D. discoideum, and further verified their effects on human leukemia K562 cells. Nitrogen-containing compounds 22 and 37 strongly inhibited cell growth in K562 leukemia cells, indicating that these compounds may be utilized as novel lead compounds for anti-leukemic agents.

Synthesis of dodec-10E-Enyl acetate - The sex pheromone of phyllonorycter blancardella (Lepidoptera: Gracillariidae)

Dodec-10E-enyl acetate has been synthesized from undecenoic acid. Field trials have shown its high attractiveness for Phyllonorycter blancardella males. 1996 Plenum Publishing Corporation.