Molecular recognition studies of selected isoalloxazines with 2,6-diamidopyridine derivatives
Triple hydrogen bond formation towards the uracil moiety of an isoalloxazine ring with 2,6-diamidopyridine derivatives has been observed in chloroform. A hydrogen bonded isoalloxazine-pyridine complex has been successfully utilised in disulfide formation
Geetanjali,Singh, Ram,Chauhan, Shive Murat Singh
p. 719 - 723
(2007/10/03)
A new and improved N-3 alkylation of 10-substituted isoalloxazines using 1,8-diazabicyclo[5.4.0]undec-7-ene in benzene
1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) has been identified as a remarkable base for the alkylation at N-3 position of 10-substituted isoalloxazines with alkyl halides in dry benzene.
Geetanjali,Singh, Ram,Chauhan
p. 613 - 620
(2007/10/03)
Microwave-assisted synthesis of 10-substituted isoalloxazines in the presence of solid acids
The microwave-enhanced synthesis of 10-substituted isoalloxazines is achieved rapidly (~4 min) and in good yield (>80-95%) via the cyclocondensation of 2-substituted aminoanilines with alloxan or N-methylalloxan monohydrate in the presence of acidic alumi
Chauhan,Singh, Ram,Geetanjali
p. 1179 - 1184
(2007/10/03)
Flavins as potential antimalarials. 2. 3-Methyl-10-(substituted-phenyl)flavins
A series of 3-methyl-10-(substituted-phenyl)flavins was prepared and tested for antimalarial activity against the lethal parasite Plasmodium vinckei in mice. Several of these analogues were found to be effective antimalarial agents. A quantitative structure-activity relationship study was undertaken with 44 analogues and no satisfactory relationship could be established.
Cowden,Halladay,Cunningham,Hunt,Clark
p. 1818 - 1822
(2007/10/02)
A new and versatile synthesis of isoalloxazines
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Sako,Kojima,Hirota,Maki
p. 1691 - 1692
(2007/10/02)
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