35804-39-8

Upstream product

• 2757-83-7 1-methylalloxan 
• 534-85-0 N-phenyl-1,2-benzenediamine 
• 4318-56-3 3-methyl-6-chlorouracil 
• 62-53-3 aniline 
• 6851-14-5 10-phenylbenzo[g]pteridine-2,4(3H,10H)-dione 
• 74-88-4 methyl iodide 
• 586-96-9 Nitrosobenzene 
• 7269-95-6 6-anilino-3-methyluracil 

Downstream Products

• 94340-35-9 N-methyl-4-phenyl-3-oxo-3,4-dihydroquinoxaline-2-carboxamide 
• 94340-37-1 N-methyl-1-phenylbenzimidazole-2-carboxamide 
• 16183-83-8 1-benzyl-3-carbamoylpyridinium ion 
• 94340-32-6 1-methyl-4-phenylimidazo<4,5-b>quinoxalin-2(4H)-one 
• 94340-30-4 1-methyl-4'-phenylspiro-2,3',5-trione 
• 2622-60-8 1-phenyl-1H-benzoimidazole 
• 110450-95-8 (3-oxo-1-phenylquinoxalin-2-ylidene)-3-methylurea 
• 71-43-2 benzene 
• 2503-55-1 N-benzylnicotinamide 
• 505-20-4 1,2-dithiane 

Relevant academic research and scientific papers

Molecular recognition studies of selected isoalloxazines with 2,6-diamidopyridine derivatives

Triple hydrogen bond formation towards the uracil moiety of an isoalloxazine ring with 2,6-diamidopyridine derivatives has been observed in chloroform. A hydrogen bonded isoalloxazine-pyridine complex has been successfully utilised in disulfide formation

Microwave-assisted synthesis of 10-substituted isoalloxazines in the presence of solid acids

The microwave-enhanced synthesis of 10-substituted isoalloxazines is achieved rapidly (～4 min) and in good yield (>80-95%) via the cyclocondensation of 2-substituted aminoanilines with alloxan or N-methylalloxan monohydrate in the presence of acidic alumi

A new and improved N-3 alkylation of 10-substituted isoalloxazines using 1,8-diazabicyclo[5.4.0]undec-7-ene in benzene

1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) has been identified as a remarkable base for the alkylation at N-3 position of 10-substituted isoalloxazines with alkyl halides in dry benzene.

Flavins as potential antimalarials. 2. 3-Methyl-10-(substituted-phenyl)flavins

A series of 3-methyl-10-(substituted-phenyl)flavins was prepared and tested for antimalarial activity against the lethal parasite Plasmodium vinckei in mice. Several of these analogues were found to be effective antimalarial agents. A quantitative structure-activity relationship study was undertaken with 44 analogues and no satisfactory relationship could be established.