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2-((Methylamino)Methyl)phenylboronic acid is a boronic acid derivative with the molecular formula C8H11BNO2. It features a phenyl group with a boronic acid functional group and a methylamino group attached to it. 2-((MethylaMino)Methyl)phenylboronic acid is widely used in organic synthesis and medicinal chemistry for its ability to form carbon-carbon bonds, particularly in the Suzuki-Miyaura coupling reaction.

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  • 365245-83-6 Structure
  • Basic information

    1. Product Name: 2-((MethylaMino)Methyl)phenylboronic acid
    2. Synonyms: 2-((MethylaMino)Methyl)phenylboronic acid
    3. CAS NO:365245-83-6
    4. Molecular Formula: C8H12BNO2
    5. Molecular Weight: 164.99738
    6. EINECS: -0
    7. Product Categories: Boronate Ester;Boronic Acid;Potassium Trifluoroborate
    8. Mol File: 365245-83-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 328.3±44.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.11±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
    8. Solubility: N/A
    9. PKA: 8.33±0.53(Predicted)
    10. CAS DataBase Reference: 2-((MethylaMino)Methyl)phenylboronic acid(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-((MethylaMino)Methyl)phenylboronic acid(365245-83-6)
    12. EPA Substance Registry System: 2-((MethylaMino)Methyl)phenylboronic acid(365245-83-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 365245-83-6(Hazardous Substances Data)

365245-83-6 Usage

Uses

Used in Organic Synthesis:
2-((Methylamino)Methyl)phenylboronic acid is used as a reagent in organic synthesis for the formation of carbon-carbon bonds. Its ability to participate in the Suzuki-Miyaura coupling reaction makes it a valuable component in creating complex organic molecules.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2-((Methylamino)Methyl)phenylboronic acid serves as a building block for the synthesis of various pharmaceuticals and biologically active molecules. Its unique structure allows for the development of new compounds with potential therapeutic applications.
Used in Material Development:
2-((Methylamino)Methyl)phenylboronic acid has potential applications in the development of new materials. Its properties can be harnessed to create innovative materials with specific characteristics for various industries.
Used in Biological Research:
2-((MethylaMino)Methyl)phenylboronic acid also serves as a tool for studying biological processes. Researchers can use 2-((Methylamino)Methyl)phenylboronic acid to investigate the interactions of molecules within biological systems, potentially leading to a better understanding of certain biological phenomena.

Check Digit Verification of cas no

The CAS Registry Mumber 365245-83-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,5,2,4 and 5 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 365245-83:
(8*3)+(7*6)+(6*5)+(5*2)+(4*4)+(3*5)+(2*8)+(1*3)=156
156 % 10 = 6
So 365245-83-6 is a valid CAS Registry Number.

365245-83-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name [2-(methylaminomethyl)phenyl]boronic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:365245-83-6 SDS

365245-83-6Relevant articles and documents

A sorbitol-selective fluorescence sensor

Swamy,Jang, Yun Jung,Park, Min Sun,Koh, Hwa Soo,Lee, Sang Kil,Yoon, Yeo Joon,Yoon, Juyoung

, p. 3453 - 3456 (2005)

A new anthracene derivative bearing two phenylboronic acid groups at the 1,8-positions was prepared and its binding properties towards sorbitol, xylitol, fructose, glucose and galactose have been studied using fluorescence analysis.

PHENYLQUINAZOLINE DERIVATIVES

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Paragraph 0319; 0320; 0321, (2013/07/19)

Novel quinazolinamide derivatives of the formula (I), in which R1-R43 and X have the meanings indicated in claim 1, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of HSP90 plays a role.

Efficient preparation of 2-aminomethylbiphenyls via suzuki-miyaura reactions

Boudreault, Pierre-Luc,Cardinal, Sébastien,Voyer, Normand

supporting information; experimental part, p. 2449 - 2452 (2010/11/18)

We prepared four 2-(aminomethyl)arylboronic acids and studied their reactivity in the Suzuki-Miyaura coupling reaction with different aryl halides. We observed significant increases in yields and shorter reaction times when the amine adjacent to the boron

MICROORGANISM KILLING COMPOUNDS

-

Page/Page column 78, (2008/12/05)

Compounds, pharmaceutical compositions, and methods of using either to kill microorganisms are disclosed.

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