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1-BIPHENYL-2-YL-N-METHYLMETHYLAMINE, also known as N-Methyl-2-biphenylmethylamine, is an organic compound with the molecular formula C15H15N. It is a derivative of biphenyl and possesses a nitrogen atom attached to a methyl group and a methylene group. 1-BIPHENYL-2-YL-N-METHYLMETHYLAMINE is known for its potential applications in the pharmaceutical industry due to its unique chemical structure and properties.

13737-31-0

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13737-31-0 Usage

Uses

Used in Pharmaceutical Industry:
1-BIPHENYL-2-YL-N-METHYLMETHYLAMINE is used as a chemical intermediate for the preparation of acyl guanidine derivatives. These derivatives are known for their potent inhibitory effects on tryptophan hydroxylase 1 (TPH1), an enzyme that plays a crucial role in the biosynthesis of serotonin. By inhibiting TPH1, these acyl guanidine derivatives can potentially be used in the development of treatments for various neurological and psychiatric disorders, such as depression, anxiety, and obsessive-compulsive disorder.

Check Digit Verification of cas no

The CAS Registry Mumber 13737-31-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,7,3 and 7 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 13737-31:
(7*1)+(6*3)+(5*7)+(4*3)+(3*7)+(2*3)+(1*1)=100
100 % 10 = 0
So 13737-31-0 is a valid CAS Registry Number.
InChI:InChI=1/C14H15N/c1-15-11-13-9-5-6-10-14(13)12-7-3-2-4-8-12/h2-10,15H,11H2,1H3

13737-31-0 Well-known Company Product Price

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  • Alfa Aesar

  • (H50765)  N-Methyl-2-biphenylmethylamine, 99%   

  • 13737-31-0

  • 250mg

  • 920.0CNY

  • Detail

  • Alfa Aesar

  • (H50765)  N-Methyl-2-biphenylmethylamine, 99%   

  • 13737-31-0

  • 1g

  • 3319.0CNY

  • Detail

13737-31-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name N-methyl-1-(2-phenylphenyl)methanamine

1.2 Other means of identification

Product number -
Other names N-methyl-2-phenylbenzylamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13737-31-0 SDS

13737-31-0Downstream Products

13737-31-0Relevant academic research and scientific papers

Synthesis of highly substituted fluorenones via metal-free TBHP-promoted oxidative cyclization of 2-(aminomethyl)biphenyls. Application to the total synthesis of nobilone

Bracher, Franz,Jourjine, Ilya A. P.,Krau?, Jürgen,Zeisel, Lukas

supporting information, p. 2668 - 2679 (2021/11/30)

Highly substituted fluorenones are readily prepared in mostly fair to good yields via metal- and additive-free TBHP-promoted cross-dehydrogenative coupling (CDC) of readily accessible N-methyl-2-(aminomethyl)biphenyls and 2-(aminomethyl)biphenyls. This methodology is compatible with numerous functional groups (methoxy, cyano, nitro, chloro, and SEM and TBS-protective groups for phenols) and was further utilized in the first total synthesis of the natural product nobilone.

Efficient preparation of 2-aminomethylbiphenyls via suzuki-miyaura reactions

Boudreault, Pierre-Luc,Cardinal, Sébastien,Voyer, Normand

supporting information; experimental part, p. 2449 - 2452 (2010/11/18)

We prepared four 2-(aminomethyl)arylboronic acids and studied their reactivity in the Suzuki-Miyaura coupling reaction with different aryl halides. We observed significant increases in yields and shorter reaction times when the amine adjacent to the boron

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