37860-51-8Relevant articles and documents
Dynamic host-guest interaction enables autonomous single molecule blinking and super-resolution imaging
Sasmal, Ranjan,Das Saha, Nilanjana,Schueder, Florian,Joshi, Divyesh,Sheeba, Vasu,Jungmann, Ralf,Agasti, Sarit S.
, p. 14430 - 14433 (2019)
Synthetic host-guest complexes are inherently dynamic as they employ weak and reversible noncovalent interactions for their recognition processes. We strategically exploited dynamic supramolecular recognition between fluorescently labeled guest molecules to complementary cucurbit[7]uril hosts to obtain stochastic switching between fluorescence ON- and OFF-states, enabling PAINT-based nanoscopic imaging in cells and tissues.
Synthesis of Highly Lipophilic Crown Ether Carboxylic Acids
Bartsch, Richard A.,Liu, Yung,Kang, Sang Ihn,Son, Byungki,Heo, Gwi Suk,et al.
, p. 4864 - 4869 (1983)
Synthetic routes to eight highly lipophilic crown ether carboxylic acids are described.Structural variations within this series of crown ether carboxylic acids include changes in the crown ether cavity size, the lipophilic group attachment site, and the b
Facile synthesis of a polyether-tethered dimeric berberine as a highly effective DNA-cleaving agent in the presence of Cu(ii) ion
Wang, Yong-Min,Zhou, Chun-Qiong,Chen, Jin-Xiang,Lin, Yan-Ling,Zeng, Wei,Kuang, Bi-Cheng,Fu, Wei-Long,Chen, Wen-Hua
, p. 1400 - 1404 (2013)
A polyether-tethered dimeric berberine was synthesized and found to be capable of efficiently converting pBR322 DNA into open circular and linear forms in the presence of Cu(ii) ions under physiological conditions, most probably via an oxidative mechanism
New C2-symmetric 2,2′-bipyridine crown macrocycles for enantioselective recognition of amino acid derivatives
Lee, Chi-Sing,Teng, Pang-Fei,Wong, Wing-Leung,Kwong, Hoi-Lun,Chan, Albert S. C.
, p. 7924 - 7930 (2005)
A series of new C2-symmetric 2,2′-bipyridine-contaning crown macrocycles 1-4 has been developed for enantiomeric recognition of amino acid derivatives. These new macrocycles have been showed to be strong complexing agents for primary organic ammonium salts (with K up to 4.83×10 5 M-1 and -ΔG0 up to 32.4 kJ mol -1) and also useful chromophores for UV-vis titration studies. These macrocyclic hosts exhibited enantioselective binding towards the (S)-enantiomer of phenylglycine methyl ester hydrochloride (Am1) with K(S)/K (R) up to 2.10 (ΔΔG0=-1.84 kJ mol -1) in CH2Cl2 with 0.25% CH3OH. The structure-binding relationship studies showed that the aromatic subunit and the ester group of the ammonium guests are both important for good enantioselectivity. In addition, the host-guest complexes have been studied using various NMR experiments.
Biscrown-annulated TTFAQ-dianthracene hybrid: Synthesis, structure, and metal ion sensing
Shao, Min,Dongare, Prateek,Dawe, Louise N.,Thompson, David W.,Zhao, Yuming
, p. 3050 - 3053 (2010)
A new fluorescence chemosensor (3) made up of a biscrown-annulated TTFAQ receptor and two anthracene fluorophores was designed and synthesized. Its solid-state structure was disclosed by X-ray crystallographic analysis, while fluorescence titrations indic
Protein micro- and nanopatterning using aminosilanes with protein-resistant photolabile protecting groups
Alang Ahmad, Shahrul A.,Wong, Lu Shin,Ul-Haq, Ehtsham,Hobbs, Jamie K.,Leggett, Graham J.,Micklefield, Jason
, p. 2749 - 2759 (2011)
An approach to the integration of nanolithography with synthetic chemical methodology is described, in which near-field optical techniques are used to selectively deprotect films formed by the adsorption of aminosilanes protected by modified 2-nitrophenylethoxycarbonyl (NPEOC) groups. The NPEOC groups are functionalized at the m- or p-position with either a tetraethyleneglycol or a heptaethylene glycol adduct. We describe the synthesis of these bioresistant aminosilanes and the characterization of the resulting photoreactive films. Photodeprotection by exposure to UV light (λ = 325 nm) yielded the amine with high efficiency, at a similar rate for all four adsorbates, and was complete after an exposure of 2.24 J cm-2. Following photodeprotection, derivatization by trifluoroacetic anhydride was carried out with high efficiency. Micropatterned samples, formed using a mask, were derivatized with aldehyde-functionalized polymer nanoparticles and, following derivatization with biotin, were used to form patterns of avidin-coated polymer particles. Fluorescence microscopy and atomic force microscopy data demonstrated that the intact protecting groups conferred excellent resistance to nonspecific adsorption. Nanometer-scale patterns were created using scanning near-field photolithography and were derivatized with biotin. Subsequent conjugation with avidin-functionalized polymer nanoparticles yielded clear fluorescence images that indicated dense attachment to the nanostructures and excellent protein resistance on the surrounding surface. These simple photocleavable protecting group strategies, combined with the use of near-field exposure, offer excellent prospects for the control of surface reactivity at nanometer resolution in biological systems and offer promise for integrating the top-down and bottom-up molecular fabrication paradigms.
Chiral synthesis via organoboranes. 46. An efficient preparation of chiral pyridino- and thiopheno-18-crown-6 ligands from enantiomerically pure C2-symmetric pyridine- and thiophenediols
Chen, Guang-Ming,Brown, Herbert C.,Ramachandran, P. Veeraraghavan
, p. 721 - 725 (1999)
Asymmetric reduction of 2,6-diacylpyridines with B- chlorodiisopinocampheylborane provides the corresponding C2-symmetric diols in very high de and ee. Asymmetric allylboration of 2,6- pyridinedicarboxaldehyde and 2,5-thiophenedicarboxaldehyde
Cucurbituril slippage: Cations as supramolecular lubricants
Ling, Xiaoxi,Masson, Eric
, p. 4866 - 4869 (2012)
The dethreading rate of a polyaminated axle flanked by two benzo-15-crown-5 stoppers from the cavity of Cucurbit[7]uril (CB[7]) was enhanced by up to 500 times in the presence of aqueous metallic and organic cations. Cations likely stabilize the highest energy transition state of the dethreading process by interacting with both crown ether and CB[7] units.
Enhancement of intramolecular photocycloaddition of bichromophoric compounds via inclusion in low-density polyethylene films
Tung, Chen-Ho,Yuan, Zhen-Yu,Wu, Li-Zhu,Wiess, Richard G.
, p. 5156 - 5161 (1999)
The photocycloaddition of tetra- and penta(ethylene glycol) labeled at the chain terminals with 2-naphthoyl groups (N-P(n)-N; n = 4 or 5) and tetra(ethylene glycol) terminated by 7-(4-methylcoumarinyl) groups (C-P4-C) has been investigated in h
Complexation of triptycene-derived macrotricyclic host with bisparaquat derivative and self-folding guest: A switchable process controlled by K + ions
Han, Ying,Guo, Jiabin,Cao, Jing,Chen, Chuanfeng
, p. 607 - 611 (2013)
Triptycene-derived cylindrical macrotricyclic host with two dibenzo-30-crown-10 cavities could form stable 1:1 complexes with not only polyether linked bisparaquat derivative but also a self-folding A-D-A guest in solution and/or solid state. Moreover, it
