38696-21-8

Basic information

• Product Name: 5-BROMO-2-(DIMETHYLAMINO)PYRIMIDINE
• Synonyms: 5-BROMO-2-(DIMETHYLAMINO)PYRIMIDINE;(5-BROMOPYRIMIDIN-2-YL)DIMETHYLAMINE;5-Bromo-N,N-dimethylpyrimidin-2-amine;2-Pyrimidinamine, 5-bromo-N,N-dimethyl-;2-broMo-N,N-diMethylpyriMidin-4-aMine;5-Bromo-N,N-dimethyl-2-pyrimidinamine;5-Bromo-2-(dimethylamino)pyrimidine 97%
• CAS NO: 38696-21-8
• Molecular Formula: C₆H₈BrN₃
• Molecular Weight: 202.05
• EINECS: 1312995-182-4
• Product Categories: Pyrimidine;Amino;Organohalides;Heterocycle-Pyrimidine series
• Mol File: 38696-21-8.mol

Chemical Properties

• Melting Point: 74-81°C
• Boiling Point: 271.959 °C at 760 mmHg
• Flash Point: 118.277 °C
• Appearance: /
• Density: 1.554 g/cm³
• Vapor Pressure: 0.006mmHg at 25°C
• Refractive Index: 1.599
• Storage Temp.: 2-8°C(protect from light)
• PKA: 2.21±0.10(Predicted)
• CAS DataBase Reference: 5-BROMO-2-(DIMETHYLAMINO)PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2-(DIMETHYLAMINO)PYRIMIDINE(38696-21-8)
• EPA Substance Registry System: 5-BROMO-2-(DIMETHYLAMINO)PYRIMIDINE(38696-21-8)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-36/37/38
• Safety Statements: 26-36/37
• WGK Germany: 3
• Hazardous Substances Data: 38696-21-8(Hazardous Substances Data)

Usage

Chemical Properties

Off-White crystal

InChI:InChI=1/C6H8BrN3/c1-10(2)6-8-3-5(7)4-9-6/h3-4H,1-2H3

Upstream product

• 5621-02-3 2-(dimethylamino)pyrimidine 
• 506-59-2 N,N-dimethylammonium chloride 
• 32779-36-5 5-Bromo-2-chloropyrimidine 
• 7752-82-1 5-bromo-2-aminopyrimidine 
• 74-88-4 methyl iodide 
• 124-40-3 dimethyl amine 
• 1072-97-5 5-bromo-2-pyridylamine 
• 53939-30-3 5-bromo-2-chloropyridine 

Downstream Products

• 1032759-30-0 N,N-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2-amine 
• 184174-10-5 N-(3-(2-(Dimethylamino)pyrimid-5-yl)phenyl)-2-amino-4-(1-pyrrolyl)aniline 
• 184173-98-6 N-Acetyl 3-(2-(dimethylamino)-5-pyrimidyl)aniline 
• 1581701-33-8 2-(dimethylamino)-N-(2-methyl-5-((4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)carbamoyl)phenyl)pyrimidine-5-carboxamide 
• 1083329-56-9 5-N-benzylamino-2-N,N-dimethylaminopyrimidine 
• 56621-99-9 5-amino-2-N,N-dimethylaminopyrimidine 
• 1392405-80-9 N²,N²-dimethyl-N⁵-phenylpyrimidine-2,5-diamine 
• 1362243-15-9 N₅-(4-(dimethylamino)phenyl)-N₂,N₂-dimethylpyrimidine-2,5-diamine 
• 1351597-83-5 C₁₇H₁₇N₅O₂S 
• 55338-76-6 2-(N,N-Dimethylamino)-5-cyanopyrimidin 
• 1025061-58-8 C₃₅H₄₂ClN₅O₄S 
• 184097-42-5 3-(2-(Dimethylamino)-5-pyrimidyl)aniline 

Relevant articles and documents

Aryl-Diadamantyl Phosphine Ligands in Palladium-Catalyzed Cross-Coupling Reactions: Synthesis, Structural Analysis, and Application

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PROBLEM TO BE SOLVED: To provide phosphoinositide 3-kinase inhibitors with a zinc binding moiety. SOLUTION: There is provided a compound represented by formula (I) in the figure. (X is S, O or the like; Y is CH, N or the like; G1 is optionally substituted N or the like; R1 and R2 are each independently H or the like; C is a substituted heterocycle or the like; B is a linear alkyl or the like; Ra and Rb together with the nitrogen atom coupled to them are morpholino or the like; G2 is an indazole ring or the like; q, r and s are independently from 0 to 1, provided that at least one of them is 1; t is from 0 to 1; n is from 0 to 4; and p is from 0 to 2.) COPYRIGHT: (C)2016,JPOandINPIT

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