387825-48-1

Basic information

• Product Name: cis-8-Methoxy-1,3-diazaspiro[4.5]decane-2,4-dione
• Synonyms: cis-8-Methoxy-1,3-diazaspiro[4.5]decane-2,4-dione
• CAS NO: 387825-48-1
• Molecular Formula: C9H14N2O3
• Molecular Weight: 198.21906
• Mol File: 387825-48-1.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: cis-8-Methoxy-1,3-diazaspiro[4.5]decane-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: cis-8-Methoxy-1,3-diazaspiro[4.5]decane-2,4-dione(387825-48-1)
• EPA Substance Registry System: cis-8-Methoxy-1,3-diazaspiro[4.5]decane-2,4-dione(387825-48-1)

Safety Data

• Hazardous Substances Data: 387825-48-1(Hazardous Substances Data)

Usage

General Description

Cis-8-Methoxy-1,3-diazaspiro[4.5]decane-2,4-dione, also known as NS-21, is a chemical compound that belongs to the class of spiro compounds. It is a heterocyclic compound containing a diazaspiro ring system and a methoxy group. cis-8-Methoxy-1,3-diazaspiro[4.5]decane-2,4-dione has potential pharmaceutical applications and has been studied for its antidepressant and anxiolytic properties. It is also being investigated for its potential use in the treatment of neurodegenerative diseases. Cis-8-Methoxy-1,3-diazaspiro[4.5]decane-2,4-dione is a promising candidate for the development of new drugs for various neurological and psychiatric disorders.

Upstream product

• 773837-37-9 sodium cyanide 
• 13482-23-0 4-methoxycyclohexanone 
• 506-87-6 ammonium carbonate 
• 18068-06-9 4-methoxycyclohexan-1-ol 
• 150-76-5 4-methoxy-phenol 
• 104-94-9 4-methoxy-aniline 
• 4342-46-5 1-amino-4-methoxycyclohexane 
• 201230-82-2 carbon monoxide 
• 77287-34-4 formamide 
• 1565500-10-8 cis-8-methoxy-1,3-diazaspiro[4.5]decane-2,4-dione 

Downstream Products

• 387825-55-0 cis-1-amino-4-methoxycyclohexane-1-carboxylic acid 
• 753441-74-6 methyl-cis-1-amino-4-methoxy-cyclohexanecarboxylate 
• 203313-25-1 spirotetramat 
• 387825-55-0 cis-1-amino-4-methoxycyclohexane-1-carboxylic acid 
• 753441-74-6 methyl cis-1-amino-4-methoxycyclohexane-1-carboxylate 
• 203312-38-3 cis-3-(2,5-dimethylphen yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-one 

Relevant articles and documents

A High-Yield and Cost-Effective Synthesis of Spirotetramat

Abstract: cis-8-Methoxy-1,3-diazaspiro[4.5]decane-2,4-dione, the key intermediate in the synthesis of spirotetramat, was synthesized by catalytic hydrogenation, oxidation, and Bucherer–Bergs reaction with 4-methoxycyclohexan-1-one as raw material. Spirotetramat was obtained in an overall yield of 20.4% by a multi-step reaction sequence including hydrolysis, esterification, acylation, intramolecular condensation, and O-acylation. The advantages of the proposed method are mild conditions, simple operation, and good to excellent yields in each step.

Novel spirodecenol compound and preparation method thereof

The invention discloses a novel spirodecenol compound and a preparation method thereof, and belongs to the technical field of pesticide synthesis. The invention adopts the key point that the novel spirodecenol compound has a structure as described in the specification. The invention also discloses a novel spirodecenol compound and a preparation method thereof. According to the invention, a novel spirodecenol compound is synthesized by a new method, a reaction process is simple and easy to operate, raw materials are cheap and easy to obtain, the reaction efficiency is high, the repeatability isgood, the insecticidal activity effect is obvious, and the spirodecenol compound has a good application prospect.

Preparation method and application of novel aminoazaheterocycles compound

The invention discloses a preparation method and application of a novel aminoazaheterocycles compound, and belongs to the technical field of applied chemistry. The technical scheme disclosed by the invention is characterized in that the novel aminoazaheterocycles compound has a following structure: a formula shown in the description. The invention further discloses the preparation method of the novel aminoazaheterocycles compound. The novel aminoazaheterocycles compound is synthesized through a new method; a reaction process is simple to operate and feasible, and raw materials are cheap and easy to obtain; the reaction efficiency is relatively high, and the repeatability is relatively good; the insecticidal activity effect is obvious.