3888-84-4

Basic information

• Product Name: 4-fluoro-3-nitrobenzenesulphonic acid
• Synonyms: 4-fluoro-3-nitrobenzenesulphonic acid;4-Fluoro-3-nitrobenzenesulfonic acid;Einecs 223-432-3
• CAS NO: 3888-84-4
• Molecular Formula: C₆H₄FNO₅S
• Molecular Weight: 221.1630632
• EINECS: 223-432-3
• Mol File: 3888-84-4.mol

Chemical Properties

• Appearance: /
• Density: 1.724 g/cm³
• Refractive Index: 1.589
• PKA: -1.27±0.50(Predicted)
• CAS DataBase Reference: 4-fluoro-3-nitrobenzenesulphonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-fluoro-3-nitrobenzenesulphonic acid(3888-84-4)
• EPA Substance Registry System: 4-fluoro-3-nitrobenzenesulphonic acid(3888-84-4)

Safety Data

• Hazardous Substances Data: 3888-84-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H4FNO5S/c7-5-2-1-4(14(11,12)13)3-6(5)8(9)10/h1-3H,(H,11,12,13)

Upstream product

• 462-06-6 fluorobenzene 
• 1493-27-2 ortho-nitrofluorobenzene 

Downstream Products

• 99069-34-8 4-(2-acetylamino-ethylsulfanyl)-3-nitro-benzenesulfonic acid 
• 6668-56-0 4-fluoro-3-nitrobenzene-1-sulfonyl chloride 
• 406233-31-6 4-fluoro-3-nitrobenzenesulfonamide 
• 406233-35-0 4-(((1R)-3-(dimethylamino)-1-((phenylthio)methyl)propyl)amino)-3-nitrobenzenesulfonamide 
• 872866-27-8 4-((R)-3-(morpholin-4-yl)-3-oxo-1-phenylsulfanylmethylpropylamino)-3-nitrobenzenesulfonamide 
• 872866-28-9 4-((R)-3-(morpholin-4-yl)-1-phenylsulfanylmethylpropylamino)-3-nitrobenzenesulfonamide 

Relevant articles and documents

CHEMICAL COMPOUNDS

The present invention relates to compounds of Formula (I): and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds inhibit Bcl-2 and/or Bcl-XL activities and may be used for the treatment of cancer.

NITROGENATED FUSED RING DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND USE OF THE SAME FOR MEDICAL PURPOSES

[Purpose] The present invention provides compounds useful as agents for the prevention or treatment of a sex hormone-dependent disease or the like. [Solution] The present invention provides nitrogen-containing fused ring derivatives represented by the following general formula (I) which has a GnRH antagonistic activity, prodrugs, salts, pharmaceutical compositions containing the same, medicinal uses thereof and the like. In the formula (I), rings A and B are independently aryl or heteroaryl; RA and RB are independently halogen, cyano, alkyl, alkylsulfonyl, -OW1, -SW1, -COW2, -NW3W4, -SO2NW3W4, aryl, etc.; RC is H or alkyl; E is oxygen atom, etc.; U is single bond or alkylene; and X is Y, -CO-Y, -SO2-Y -S-(alkylene)-Y, -O-(alkylene)-Y, -SO2-(alkylene)-Y, etc.; Y is Z or amino, etc.; and Z is cycloalkyl, heterocycloalkyl, aryl, heteroaryl, etc.

METHOD AND COMPOSITIONS FOR TREATING HIV INFECTIONS

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