389889-62-7

Basic information

• Product Name: (R)-1-N-Boc-3-(2-hydroxyethyl)piperidine
• Synonyms: (R)-1-N-Boc-3-(2-hydroxyethyl)piperidine;(R)-3-(2-Hydroxyethyl)piperidine-1-carboxylic acid tert-butyl ester;(R)-tert-Butyl 3-(2-hydroxyethyl)piperidine-1-carboxylate;1-Piperidinecarboxylic acid, 3-(2-hydroxyethyl)-, 1,1-dimethylethyl ester, (3R)-
• CAS NO: 389889-62-7
• Molecular Formula: C12H23NO3
• Molecular Weight: 229.32
• Mol File: 389889-62-7.mol

Chemical Properties

• Boiling Point: 324.1 °C at 760 mmHg
• Flash Point: 149.8 °C
• Appearance: /
• Density: 1.043 g/cm³
• Vapor Pressure: 1.97E-05mmHg at 25°C
• Refractive Index: 1.478
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (R)-1-N-Boc-3-(2-hydroxyethyl)piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-N-Boc-3-(2-hydroxyethyl)piperidine(389889-62-7)
• EPA Substance Registry System: (R)-1-N-Boc-3-(2-hydroxyethyl)piperidine(389889-62-7)

Safety Data

• Hazardous Substances Data: 389889-62-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(R)-1-N-Boc-3-(2-hydroxyethyl)piperidine is used as a synthetic intermediate for the development of pharmaceuticals, leveraging its unique structure and the Boc protecting group to facilitate selective chemical reactions that can lead to the creation of new medicinal compounds.
Used in Organic Synthesis:
In the field of organic synthesis, (R)-1-N-Boc-3-(2-hydroxyethyl)piperidine serves as a key building block, contributing to the formation of complex organic molecules. Its presence of the hydroxyethyl group allows for further functionalization, making it a versatile component in the synthesis of a variety of organic compounds.
Used in Chiral Chemistry:
(R)-1-N-Boc-3-(2-hydroxyethyl)piperidine is utilized in chiral chemistry for the study and creation of enantiomerically pure compounds. The specific (R)-enantiomer can be crucial in applications where the stereochemistry of a molecule significantly influences its biological activity or pharmacological properties.

InChI:InChI=1/C12H23NO3/c1-12(2,3)16-11(15)13-7-4-5-10(9-13)6-8-14/h10,14H,4-9H2,1-3H3/t10-/m1/s1

Upstream product

• 188723-32-2 t-butyl (3R)-3-(2-ethoxy-2-oxoethyl)tetrahydropyridine-1(2H)-carboxylate 

Downstream Products

• 1039361-81-3 tert-butyl (R)-3-(2-oxoethyl)piperidine-1-carboxylate 

Relevant articles and documents

Ester derivatives

This invention relates to compounds which exhibit selective muscarinic M3 receptor antagonism, have little side effects, are suitable for inhalation therapy and are useful as treating agents of respiratory system diseases, of the general formula (I); 1[in which A signifies a group expressed by a formula (a0) or (b0); 2Ar signifies optionally substituted aryl or heteroaryl; B1 and B2 signify aliphatic hydrocarbon; R1 signifies fluorine-substituted cycloalkyl; R2, R3 and R4 signify lower alkyl, single bond or alkylene bonded to B1, or R2 and R3 are united to signify alkylene; R5 and R7 signify hydrogen, lower alkyl, or a single bond or alkylene bonded to B2; R6 signifies hydrogen, lower alkyl or a group expressed as —N(R8)R9; and X?signifies an anion].