389889-80-9

Basic information

• Product Name: 1-BOC-4-HYDROXY-4-(HYDROXYMETHYL)-PIPERIDINE
• Synonyms: 1-BOC-4-HYDROXY-4-(HYDROXYMETHYL)-PIPERIDINE;4-Hydroxy-4-hydroxyMethylpiperidine-1-carboxylic acid tert-butyl ester;1-Boc-4-hydroxy-4-(hydrox...;tert-butyl 4-hydroxy-4-(hydroxymethyl)piperidine-1-carboxylate
• CAS NO: 389889-80-9
• Molecular Formula: C₁₁H₂₁NO₄
• Molecular Weight: 231.29
• EINECS: 200-589-5
• Mol File: 389889-80-9.mol

Chemical Properties

• Boiling Point: 350.9±27.0 °C(Predicted)
• Appearance: /
• Density: 1.164±0.06 g/cm3(Predicted)
• PKA: 14.06±0.20(Predicted)
• CAS DataBase Reference: 1-BOC-4-HYDROXY-4-(HYDROXYMETHYL)-PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BOC-4-HYDROXY-4-(HYDROXYMETHYL)-PIPERIDINE(389889-80-9)
• EPA Substance Registry System: 1-BOC-4-HYDROXY-4-(HYDROXYMETHYL)-PIPERIDINE(389889-80-9)

Safety Data

• Hazardous Substances Data: 389889-80-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
1-BOC-4-HYDROXY-4-(HYDROXYMETHYL)-PIPERIDINE is used as a reagent for the production of pharmaceuticals, leveraging its protected hydroxyl and hydroxymethyl groups to facilitate selective reactions in the synthesis of complex drug molecules.
Used in Organic Synthesis:
In the field of organic chemistry, 1-BOC-4-HYDROXY-4-(HYDROXYMETHYL)-PIPERIDINE serves as a key intermediate, enabling the creation of a variety of biologically active compounds through its selective reactivity and stability.
Used in Research and Development:
1-BOC-4-HYDROXY-4-(HYDROXYMETHYL)-PIPERIDINE is utilized in research and development for the exploration of new chemical pathways and the discovery of novel compounds with potential applications in medicine and other industries.
Used in Chemical Intermediates Production:
As a chemical intermediate, 1-BOC-4-HYDROXY-4-(HYDROXYMETHYL)-PIPERIDINE is employed in the synthesis of other complex organic compounds, contributing to the development of new materials and products across various chemical industries.

Upstream product

• 159635-49-1 tert-butyl 4-methylidenepiperidine-1-carboxylate 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 19867-34-6 N-benzyl-1-oxa-6-azaspiro[2,5]-octane 
• 92197-36-9 4-hydroxy-4-(hydroxymethyl)-1-(phenylmethyl)piperidine 
• 89584-31-6 4-(hydroxymethyl)piperidin-4-ol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 297172-16-8 (4-methylpiperidin-4-yl)methanol 
• 189442-87-3 ethyl tert-butyl 4-methylpiperidine-1,4-dicarboxylate 
• 103039-88-9 ethyl 4-methylpiperidine-4-carboxylate 

Downstream Products

• 1257300-52-9 1,1-dimethylethyl 1,3-dioxa-2-thia-8-azaspiro[4.5]decane-8-carboxylate 2,2-dioxide 

Relevant articles and documents

HEPATITIS B ANTIVIRAL AGENTS

The present invention includes a method of inhibiting, suppressing or preventing HBV infection in an individual in need thereof, comprising administering to the individual a therapeutically effective amount of at least one compound of the invention.

PHENYL-HETEROARYL DERIVATIVES AND METHODS OF USE THEREOF

The present invention provides phenyl-heteroaryl derivatives of Formula (I) and pharmaceutically acceptable salts thereof. These compounds are useful in the treatment of RAGE-mediated diseases such as Alzheimer's Disease. The present invention further relates to methods for the preparation of compounds of Formula (I) and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising such compounds, and the use of such compounds and/or pharmaceutical compositions in treating RAGE-mediated diseases.

Ester derivatives

This invention relates to compounds which exhibit selective muscarinic M3 receptor antagonism, have little side effects, are suitable for inhalation therapy and are useful as treating agents of respiratory system diseases, of the general formula (I); 1[in which A signifies a group expressed by a formula (a0) or (b0); 2Ar signifies optionally substituted aryl or heteroaryl; B1 and B2 signify aliphatic hydrocarbon; R1 signifies fluorine-substituted cycloalkyl; R2, R3 and R4 signify lower alkyl, single bond or alkylene bonded to B1, or R2 and R3 are united to signify alkylene; R5 and R7 signify hydrogen, lower alkyl, or a single bond or alkylene bonded to B2; R6 signifies hydrogen, lower alkyl or a group expressed as —N(R8)R9; and X?signifies an anion].