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CAS

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390406-53-8

1-BOC-3-(3,4-DICHLOROPHENYL)-3-HYDROXYPYRROLIDINE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 390406-53-8 Structure

  • Basic information

    1. Product Name: 1-BOC-3-(3,4-DICHLOROPHENYL)-3-HYDROXYPYRROLIDINE
    2. Synonyms: 1-BOC-3-(3,4-DICHLOROPHENYL)-3-HYDROXYPYRROLIDINE;1-Boc-3-(3,4-dichlorophenyl)-3-pyrrolidinol
    3. CAS NO:390406-53-8
    4. Molecular Formula: C15H19Cl2NO3
    5. Molecular Weight: 332.225
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 390406-53-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-BOC-3-(3,4-DICHLOROPHENYL)-3-HYDROXYPYRROLIDINE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-BOC-3-(3,4-DICHLOROPHENYL)-3-HYDROXYPYRROLIDINE(390406-53-8)
    11. EPA Substance Registry System: 1-BOC-3-(3,4-DICHLOROPHENYL)-3-HYDROXYPYRROLIDINE(390406-53-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 390406-53-8(Hazardous Substances Data)

390406-53-8 Usage

Chemical Class

Pyrrolidine derivatives

Physical State

White solid

Molecular Weight

330.24 g/mol (calculated from the molecular formula)

Appearance

White crystalline solid

Melting Point

Not provided, but typically pyrrolidine derivatives have a defined melting point

Solubility

Not provided, but generally soluble in organic solvents like methanol, ethanol, or acetone

Stability

Stable under normal conditions, but sensitive to heat, light, and moisture

Reactivity

Reacts with various reagents in organic synthesis

Synthesis

Often used as a building block for the preparation of pharmaceuticals and agrochemicals

Applications

Under active research and development for potential drug candidates for various medical conditions

Safety

Handle with care, as the safety profile is not provided in the material

Storage

Store in a cool, dry place, away from heat, light, and moisture

Regulatory Status

Not provided, but may be subject to specific regulations depending on the intended use and location

Environmental Impact

Not provided, but should be considered when handling and disposing of the compound

Check Digit Verification of cas no

The CAS Registry Mumber 390406-53-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,9,0,4,0 and 6 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 390406-53:
(8*3)+(7*9)+(6*0)+(5*4)+(4*0)+(3*6)+(2*5)+(1*3)=138
138 % 10 = 8
So 390406-53-8 is a valid CAS Registry Number.

390406-53-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl 3-(3,4-dichlorophenyl)-3-hydroxypyrrolidine-1-carboxylate

1.2 Other means of identification

Product number -
Other names tert-butyl 3-(3,4-dichlorophenyl)-3-hydroxypyrrolidin-1-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:390406-53-8 SDS

390406-53-8Relevant articles and documents

DISUBSTITUTED PHENYLPYRROLIDINES AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION

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Page/Page column 26, (2010/08/03)

The present invention relates to the use of compounds which increase extracellular levels of catecholamines, dopamine and norepinephrine, in cerebral cortical areas of the mammalian brain, and more specifically to the use of 3-disubstituted phenyl-1-pyrrolidinols for the treatment of central nervous system disorders.

NEW DISUBSTITUTED PHENYLPYRROLIDINES AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION

-

Page/Page column 34, (2009/01/24)

The present invention provides compounds which increase extracellular levels of catecholamines, dopamine and norepinephrine, in cerebral cortical areas of the mammalian brain, and more specifically to the use of 3-(disubstituted aryl)-pyrrolidines for the treatment of central nervous system disorders.

Discovery and initial structure-activity relationships of trisubstituted ureas as thrombin receptor (PAR-1) antagonists

Barrow, James C,Nantermet, Philippe G,Selnick, Harold G,Glass, Kristen L,Ngo, Phung L,Young, Mary Beth,Pellicore, Janetta M,Breslin, Michael J,Hutchinson, John H,Freidinger, Roger M,Condra, Cindra,Karczewski, Jerzy,Bednar, Rodney A,Gaul, Stanley L,Stern, Andrew,Gould, Robert,Connolly, Thomas M

, p. 2691 - 2696 (2007/10/03)

Thrombin is the most potent agonist of platelet activation, and its effects are predominantly mediated by platelet thrombin receptors. Therefore, antagonists of the thrombin receptor have potential utility for the treatment of thrombotic disorders. Screening of combinatorial libraries revealed 2 to be a potent antagonist of the thrombin receptor. Modifications of this structure produced 11k, which inhibits thrombin receptor stimulated secretion and aggregation of platelets.

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