39341-78-1

Basic information

• Product Name: 2-n-hexyl-5-n-propylresorcinol
• Synonyms: 2-n-hexyl-5-n-propylresorcinol;2-hexyl-5-propylbenzene-1,3-diol
• CAS NO: 39341-78-1
• Molecular Formula: C₁₅H₂₄O₂
• Molecular Weight: 236.3499
• Mol File: 39341-78-1.mol

Chemical Properties

• Boiling Point: 379.2°Cat760mmHg
• Flash Point: 174.4°C
• Appearance: /
• Density: 1.008g/cm³
• Vapor Pressure: 2.74E-06mmHg at 25°C
• Refractive Index: 1.528
• CAS DataBase Reference: 2-n-hexyl-5-n-propylresorcinol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-n-hexyl-5-n-propylresorcinol(39341-78-1)
• EPA Substance Registry System: 2-n-hexyl-5-n-propylresorcinol(39341-78-1)

Safety Data

• Hazardous Substances Data: 39341-78-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Applications:
2-n-hexyl-5-n-propylresorcinol is used as a bioactive compound for its antimicrobial properties, which can be utilized in the development of new drugs to combat various infections.
Used in Cosmetic Applications:
2-n-hexyl-5-n-propylresorcinol is used as an ingredient in cosmetic products for its antimicrobial and antifungal effects, which can help maintain skin health and prevent infections.
Used in Food Industry:
2-n-hexyl-5-n-propylresorcinol is used as a flavor ingredient for its characteristic spicy taste, adding a unique flavor profile to food and drinks.
Used in Food Preservation:
2-n-hexyl-5-n-propylresorcinol is used as a natural preservative for its antimicrobial properties, helping to extend the shelf life of food products by inhibiting the growth of harmful microorganisms.
Used in Beverage Industry:
2-n-hexyl-5-n-propylresorcinol is used as a flavor enhancer in beverages, providing a spicy taste sensation that can be likened to "biting into a hot chili pepper".

InChI:InChI=1/C15H24O2/c1-3-5-6-7-9-13-14(16)10-12(8-4-2)11-15(13)17/h10-11,16-17H,3-9H2,1-2H3

Upstream product

• 7311-34-4 3,5-dimethoxybenzaldehdye 
• 640734-50-5 3-carbomethoxy-5-hexyl-4,6-dimethoxy-2-propylbenzoic acid 
• 640734-51-6 4,6-dimethoxy-5-hexyl-2-propyl-1,3-benzenedioic acid 
• 58576-36-6 1,3-Dimethoxy-2-hexyl-5-propylbenzene 
• 123-39-7 N-Methylformamide 
• 110-53-2 1-Bromopentane 
• 41395-10-2 1,3-dimethoxy-5-propylbenzene 
• 89711-22-8 2-Hexyl-3-methoxy-5-propyl-phenol 
• 111-25-1 1-bromo-hexane 
• 55136-70-4 3-methoxy-5-propylphenol 

Relevant articles and documents

High-Yielding Total Synthesis of Sexually Deceptive Chiloglottones and Antimicrobial Dialkylresorcinols through an Organocatalytic Reductive Coupling Reaction

Biologically important, less-explored natural products of sexually deceptive chiloglottones, antimicrobial dialkylresorcinols, and their many analogues were synthesized in very good yields in a sequential two-pot manner by using an "organocatalytic reductive coupling reaction" as the key step. Sexually deceptive chiloglottones, antimicrobial dialkylresorcinols, and their many analogues are synthesized in very good yields in a sequential two-pot manner by using an "organocatalytic reductive coupling reaction" as the key step.

Ion pairing effects on the regioselectivity of arylic versus benzylic C-O bond reductive cleavage: synthetic applications

The regioselectivity of the reductive cleavage of 3,4,5-trimethoxybenzyl methyl ether strongly depends on the alkali metal employed as a reducing agent and solvent effects. Reactions run using Na as a reducing agent led to aromatic C(4)-O bond cleavage, whilst reductions run in the presence of Na/15-crown-5, or using Li as a reducing agent, led to highly regioselective benzylic C-O bond cleavage. This regioselectivity turnaround is discussed in terms of major solvent effects affecting the fragmentation paths of a common reaction intermediate. Synthetic applications of these findings led to the synthesis of biologically active compounds, like 2,5-dialkyl-substituted resorcinols, or 1-(3,4,5-trimethoxyphenyl)-2-arylethanes structurally related to combretastatin.

A total synthesis of the antibiotic DB-2073

A convergent aromatic annulation strategy based on the Michael addition of the dimethyl-1,3-acetonedicarboxylate 1 anion to 2-hexynal 2, followed by a regiocontrolled Dieckmann-type cyclization, has been applied to a total synthesis of the antibiotic, DB-2073 I. This tandem annulation reaction generates the fully substituted aromatic intermediate 3, which was transformed by a five-step sequence to I.

A convenient, practical synthesis of substituted resorcinols: Synthesis of DB-2073 and olivetol

A wide variety of easily accesible 1,3-cyclohexanediones are readily transformed to substituted dimethyl resorcinols with iodine and methanol.

A Regiocontrolled Annulation Approach to Highly Substituted Aromatic Compounds

The thermal combination of cyclobutenone derivatives with heterosubstituted acetylenes provides a regiocontrolled route to highly substitutted aromatic compounds