40589-84-2

Basic information

• Product Name: 1-(1-phenylethyl)urea
• Synonyms: 1-(1-phenylethyl)urea;(1-Phenyl-ethyl)-urea
• CAS NO: 40589-84-2
• Molecular Formula: C₉H₁₂N₂O
• Molecular Weight: 164.20438
• Mol File: 40589-84-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(1-phenylethyl)urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-phenylethyl)urea(40589-84-2)
• EPA Substance Registry System: 1-(1-phenylethyl)urea(40589-84-2)

Safety Data

• Hazardous Substances Data: 40589-84-2(Hazardous Substances Data)

Upstream product

• 556-89-8 nitrourea 
• 618-36-0 rac-methylbenzylamine 
• 100-42-5 styrene 
• 57-13-6 urea 
• 82485-77-6 N-(1-phenylethyl)cyanamide 
• 14649-03-7 1-phenylethylisocyanate 
• 98-86-2 acetophenone 

Downstream Products

• 19035-03-1 N-benzyl-N'-(1-phenylethyl)urea 
• 147169-48-0 (R,S)-N-(tert-butyloxycarbonyl)-α-methylbenzylamine 
• 82485-79-8 N-aminomethyl-1-phenethyl amine 
• 86918-15-2 α,α’-dimethyl-1,3-dibenzylurea 
• 40589-73-9 N-Phenylacetyl-N'-(1-phenylethyl)-harnstoff 
• 40589-70-6 N-Butyryl-N'-(1-phenylethyl)-harnstoff 
• 40589-68-2 N-Acetyl-N'-(1-phenylethyl)-harnstoff 
• 40589-71-7 N-Pentanoyl-N'-(1-phenylethyl)-harnstoff 
• 40589-69-3 N-(1-Phenylethyl)-N'-propionyl-harnstoff 
• 109092-27-5 5,5-diethyl-1-(1-phenyl-ethyl)-barbituric acid 

Relevant articles and documents

One-pot, solvent-free access to unsymmetrical ureas by palladium-catalysed reductive alkylation using molecular hydrogen

Palladium-catalysed reductive alkylation of monosubstituted ureas has been studied in the presence of aldehydes and using molecular hydrogen as a clean reductant. Unsymmetrical N,N′-disubstituted ureas were formed in good to excellent isolated yields (60-93 %) without the production of salt waste. This reaction was incorporated to a one-pot, solvent-free sequence involving the alkylation of monosubstituted ureas generated in situ from the corresponding amines. Unsymmetrical N,N′-disubstituted ureas were prepared in 60-93 % isolated yield by palladium-catalysed reductive alkylation of monosubstituted ureas using aldehydes as alkylating agents and molecular hydrogen as a clean reductant. A one-pot, solvent-free sequence was also developed from the corresponding amines. Copyright

Amidomercuriation: A General Addition of Amides and Related Compounds to Olefins

The addition of different carboxamides and related compounds such as urethane or urea to olefins using mercury(II) nitrate followed by sodium borohydride reduction to give the corresponding N-substituted amides, urethanes, or ureas, respectively, is described.The monoalkylated ureas, through the same amidomercuriation-demercuriation procedure, yield symmetrical and unsymmetrical N,N'-disubstituted ureas.This amidomercuriation-demercuriation process provides a new, convenient, and general method for the Markovnikov amidation of carbon-carbon double bonds.

Some Extensions of von Braun (BrCN) Reaction on Organic Bases: Part II

Extensions of von Braun Cyanogen bromide reaction on Ephedra alkaloids and simpler bases have resulted in synthesis of substituted oxazolidines and a whole series of nitrogen analogues of ephedrine, desoxy ephedrine and simpler amines.The general applicability and limitations of such extension of the reaction are also discussed. - Key words: von Braun Cyanogen Bromide Reaction

Amidomercuration; a New and Regiospecific Addition of Amides to Olefins

The reaction of olefins with anhydrous mercury(II) nitrate in the presence of primary amides leads, after in situ alkaline sodium borohydride reduction, to the corresponding N-substituted amides; this procedure provides a new, convenient method for the Markovnikov amidation of carbon-carbon double bonds.