Asymmetric hydroamination of acrylonitrile derivatives catalyzed by Ni(II)-complexes
Chiral ferrocenyl tridentate phosphine ligands were synthesized and used in asymmetric hydroamination reactions catalyzed by Ni(II)-complexes. Compounds of the type [Ni(PPP)L]2+, where L is a chloride, solvent molecule or a coordinated substrate, were isolated. The efficiency of these complexes in asymmetric catalysis was high when aliphatic or aromatic amines were reacted with electron-poor olefins, especially with acrylonitrile derivatives. This hydroamination reaction affords up to 95% enantioselectivity at -80 °C for the addition of morpholine to methacrylonitrile (69% ee at room temperature).
Fadini, Luca,Togni, Antonio
experimental part
p. 2555 - 2562
(2009/04/06)
Structural variation, dynamics, and catalytic application of palladium(ii) complexes of di-N-heterocyclic carbene-amine ligands
A series of palladium(ii) complexes incorporating di-NHC-amine ligands has been prepared and their structural, dynamic and catalytic behaviour investigated. The complexes [trans-(κ2-tBuCN(Bn) CtBu)PdCl2] (12) an
Houghton, Jennifer,Dyson, Gavin,Douthwaite, Richard E.,Whitwood, Adrian C.,Kariuki, Benson M.
p. 3065 - 3073
(2008/02/09)
Aza-Michael Reactions in Ionic Liquids. A Facile Synthesis of β-Amino Compounds
Electron-deficient olefins undergo smoothly aza-Michael reactions with a wide range of amines in ionic liquids in the absence of any acid catalyst to produce the corresponding β-amino compounds in excellent yields with high 1,4-selectivity. The recovered ionic liquids can be reused in subsequent reactions without loss of activity. Owing to the high polarity of ionic liquids, the enones show enhanced reactivity thereby reducing reaction times and improving the yields significantly.
Yadav,Reddy,Basak,Narsaiah
p. 988 - 989
(2007/10/03)
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