409341-03-3

Basic information

• Product Name: TERT-BUTYL 4-HYDROXY-2-OXOPYRROLIDINE-1-CARBOXYLATE
• Synonyms: (+/-)-N-BOC-4-HYDROXY-2-PYRROLIDINONE;TERT-BUTYL 4-HYDROXY-2-OXOPYRROLIDINE-1-CARBOXYLATE;1-Pyrrolidinecarboxylic acid, 4-hydroxy-2-oxo-
• CAS NO: 409341-03-3
• Molecular Formula: C9H15NO4
• Molecular Weight: 201.22
• Mol File: 409341-03-3.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: TERT-BUTYL 4-HYDROXY-2-OXOPYRROLIDINE-1-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL 4-HYDROXY-2-OXOPYRROLIDINE-1-CARBOXYLATE(409341-03-3)
• EPA Substance Registry System: TERT-BUTYL 4-HYDROXY-2-OXOPYRROLIDINE-1-CARBOXYLATE(409341-03-3)

Safety Data

• Hazardous Substances Data: 409341-03-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
TERT-BUTYL 4-HYDROXY-2-OXOPYRROLIDINE-1-CARBOXYLATE is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of various medicinal compounds.
Used in Agrochemical Industry:
Similarly, in the agrochemical sector, TERT-BUTYL 4-HYDROXY-2-OXOPYRROLIDINE-1-CARBOXYLATE serves as an intermediate in the synthesis of agrochemicals, playing a role in the creation of substances that can enhance crop protection and productivity.

Upstream product

• 924-49-2 DL-4-amino-3-hydroxybutyric acid 
• 24424-99-5 di-tert-butyl dicarbonate 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 73602-61-6 triethylamine tris(hydrogen fluoride) 

Downstream Products

• 141293-14-3 N-(tert-butoxycarbonyl)pyrrol-2(5H)-one 

Relevant articles and documents

Process for the preparation of substituted pyrrolidine neuraminidase inhibitors

A process for the preparation of neuraminidase inhibitors having structural formula (28) or therapeutically acceptable salts thereof, in which R1 is alkyl, cycloalkyl, cycloalkylalkyl, or arylalkyl; R2 is alkyl, cycloalkyl, cycloalky

An efficient scalable process for the synthesis of N-Boc-2-tert-butyldimethylsiloxypyrrole

A safe, reliable and scalable process for the preparation of N-Boc-2-tert-butyldimethylsiloxy-pyrrole (TBSOP) is described. In a three-step, one-pot sequence (±)-4-amino-3-hydroxybutyric acid was converted to N-Boc-4-hydroxy-2-pyrrolidinone. This stable crystalline product was isolated by filtration directly from the reaction mixture. Dehydration followed by enolization and silylation produced the target compound without the need for chromatographic purification. The process was demonstrated in the pilot plant to make multikilogram quantities of material in 85% overall yield.