422517-67-7

Basic information

• Product Name: 1-(4-Nitrobenzyl)piperazine dihydrochloride
• Synonyms: 4-[(Piperazin-1-yl)methyl]nitrobenzene dihydrochloride;1-(4-Nitrobenzyl)piperazinedihydrochloride97%;1-(4-Nitrobenzyl)piperazine*2HCl;1-(4-Nitrobenzyl)piperazine*2HCI
• CAS NO: 422517-67-7
• Molecular Formula: C11H15N3O2.2HCl
• Molecular Weight: 257.72
• Mol File: 422517-67-7.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(4-Nitrobenzyl)piperazine dihydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Nitrobenzyl)piperazine dihydrochloride(422517-67-7)
• EPA Substance Registry System: 1-(4-Nitrobenzyl)piperazine dihydrochloride(422517-67-7)

Safety Data

• Hazardous Substances Data: 422517-67-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-(4-Nitrobenzyl)piperazine dihydrochloride is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to increase the reactivity of the piperazine molecule, thereby contributing to the development of drugs with enhanced pharmacological properties.
Used in Drug Development:
As a building block in the synthesis of pharmaceuticals, 1-(4-Nitrobenzyl)piperazine dihydrochloride is utilized in drug development to create new and improved medications with potentially better efficacy and safety profiles.
Used in Pesticide Industry:
Given its origin as a derivative of piperazine, which is also found in pesticides, 1-(4-Nitrobenzyl)piperazine dihydrochloride may be used as a component in the development of new pesticides, potentially offering more effective and environmentally friendly solutions for pest control.

Upstream product

• 7542-23-6 piperazine hydrochloride 
• 100-14-1 4-nitrobenzyl chloride 
• 130636-61-2 1-[(4-nitrophenyl)methyl]-4-tert-butyloxycarbonylpiperazine 
• 110-85-0 piperazine 

Relevant articles and documents

Aralkyl-alcohol peiperazine derivatives adn their uses as antidepressant

Aryl alkanol piperazine derivatives of the formula and pharmaceutical compositions comprising the same. Also disclosed are methods for treating depression using the pharmaceutical compositon. Compounds of the invention have excellent dual inhibitory actions to the uptake of the mono-amines neurotransmitter, good antidepressant activities and minor side effects.

Design, synthesis, and biological testing of thiosalicylamides as a novel class of calcium channel blockers

The current research aimed to investigate the importance of the heterocyclic ring system in the structure of the cardiovascular drug diltiazem for its calcium channel blocking activity. The manuscript describes the design, synthesis, and biological testin

Substituted indolinones, preparation thereof and their use as pharmaceutical compositions

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Calcium channel blockers

The invention involves the identification of a family of compounds which block calcium channels. The compounds can be formulated in pharmaceutical carriers and administered to subjects. The compounds are useful for treating disorders associated with calci