4274-38-8 Usage
Uses
Used in Pharmaceutical Industry:
3-AMINO-4-MERCAPTOBENZOTRIFLUORIDE HYDROCHLORIDE is used as an intermediate compound for the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs with specific therapeutic properties.
Used in Chemical Synthesis:
In the chemical industry, 3-AMINO-4-MERCAPTOBENZOTRIFLUORIDE HYDROCHLORIDE is used as a building block for the synthesis of complex organic molecules. Its reactivity and functional groups make it a valuable asset in creating a wide range of chemical products.
Specific Application:
3-AMINO-4-MERCAPTOBENZOTRIFLUORIDE HYDROCHLORIDE is used as a synthetic precursor for the production of 6-trifluoromethyl-4H-1,4-benzothiazines. This application takes advantage of the compound's ability to undergo condensation and oxidative cyclization with β-di-carbonyl compounds, leading to the formation of the desired benzothiazine derivatives. These derivatives have potential applications in various fields, including pharmaceuticals and materials science, due to their unique chemical and biological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 4274-38-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,7 and 4 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 4274-38:
(6*4)+(5*2)+(4*7)+(3*4)+(2*3)+(1*8)=88
88 % 10 = 8
So 4274-38-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H10F3N5O.ClH/c10-9(11,12)18-6-3-1-5(2-4-6)16-8(15)17-7(13)14;/h1-4H,(H6,13,14,15,16,17);1H
4274-38-8Relevant articles and documents
Synthesis of 6-trifluoromethyl-4h-1,4-benzothiazines as possible anticancer agents
Gupta,Kumar, Rakesh
, p. 19 - 24 (1986)
The synthesis of 6-trifluoromethyl-4H-1,4-benzothiazines is reported by the condensation and oxidative cyclization of 2-amino-4-trifluoromethylbenzenethiol hydrochloride with β-di- carbonyl compounds. All the newly synthesized compounds have been characte
Process for preparing chloromethyl thiazoles or oxazoles, and intermediates for use therein
-
, (2008/06/13)
Chloromethyl group substituted heterocyclic compounds of the formulae STR1 wherein X is O or S; Y together with the two carbons to which Y is attached forms phenyl, pyridyl or pyrimidyl, each of which may be substituted by R; R is one of iodo or trifluoromethylthio or one or two of fluoro, chloro, bromo, (C1 -C4)alkyl, (C1 -C4)alkoxy, (C1 -C4)alkylthio, (C1 -C4)alkylsulfinyl, (C1 -C4)alkylsulfonyl or trifluoromethyl; and R1 is hydrogen or R, are prepared by reacting a bifunctional compound of the formulae STR2 with a 2-chloro-1,1,1-tri(C1 -C6)alkoxyethane. Most of the compounds of formulae I and II are novel. These compounds are intermediates of use in the preparation of compounds having pharmaceutical activity. The 2-chloro-1,1,1-tri(C1 -C6)alkoxyethanes are prepared from the corresponding tri(C1 -C6)alkoxyethanes by chlorination with N-chlorosuccinimide or with chlorine in pyridine and a chlorohydrocarbon cosolvent.